ABSTRACT: Complete Nucleotide Sequence of a ST410 Escherichia coli strain carrying blaNDM-5 on an IncF multidrug resistance plasmid and blaOXA-181 on an IncX3 plasmid
Project description:The study aimed to characterize plasmids mediating carbepenem resistance in Klebsiella pneumoniae in Pretoria, South Africa. We analysed 56 K. pneumoniae isolates collected from academic hospital around Pretoria. Based on phenotypic and molecular results of these isolates, 6 representative isolates were chosen for further analysis using long reads sequencing platform. We observed multidrug resistant phenotype in all these isolates, including resistance to aminoglycosides, tetracycline, phenicol, fosfomycin, floroquinolones, and beta-lactams antibiotics. The blaOXA-48/181 and blaNDM-1/7 were manily the plasmid-mediated carbapenemases responsible for carbapenem resistance in the K. pneumoniae isolates in these academic hospitals. These carbapenemase genes were mainly associated with plasmid replicon groups IncF, IncL/M, IncA/C, and IncX3. This study showed plasmid-mediated carbapenemase spread of blaOXA and blaNDM genes mediated by conjugative plasmids in Pretoria hospitals.
2019-10-17 | GSE138949 | GEO
Project description:Multidrug-resistant Salmonella enterica serovar London carrying blaNDM-1 encoding plasmid from Singapore
| PRJNA576021 | ENA
Project description:Providencia stuartii carrying blaNDM on an IncC plasmid
| PRJNA948429 | ENA
Project description:First genome sequence of carbapenem-resistant Citrobacter koseri carrying blaOXA-181 isolated from sludge.
Project description:Hospital outbreak of blaOXA-181 positive Enterobacteriaceae
| PRJNA545001 | ENA
Project description:Genetic characterization of IncN2 and IncF plasmid harboring blaNDM-1 in carbapenem-resistant Enterobacteriaceae from Songklanagarind hospital, Thailand
