Ontology highlight
ABSTRACT:
PROVIDER: PRJNA417474 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:Sperm contains essential proteins for interaction with eggs, however, there are only several sperm proteins reported with important role in fertilization, and gamete proteomics are limited in marine invertebrate species. We present here a sperm proteomic profile of marine mussel Mytilus galloprovincialis. There are 816 proteins were successfully identified by LC-MS/MS based on 1-DE SDS-PAGE. Many of the identifications are relevant to sperm cell physiology and mtDNA functioning. The results will contribute to better understand the proteins involved in fertilization in M. galloprovincialis, as well as the other marine invertebrate species.
2015-07-17 | PXD001665 | Pride
Project description:Proteome analysis of the surface matrix of chitinous barrier membranes of the tunicate Ciona intestinalis Type A, a marine filter-feeding invertebrate chordate. This chitinous membrane separate food microbes from the gut epithelium, as a physical barrier. As controls, we used mucus cords from the esophagus.
2018-07-24 | PXD010503 | JPOST Repository
Project description:Despite recent advances in pluripotent stem cell-based approaches to induce skeletal cells, recapitulating human limb skeletal development in terms of structure and longitudinally oriented growth remains an unresolved challenge. Here, we report a method to differentiate human pluripotent stem cells into region-specific skeletal organoids harboring GDF5+PRG4+ interzone/articular chondrocyte progenitors (IZ/ACPs) and SP7+ growth plate chondrocytes (GPCs) via PRRX1⁺ limb-bud mesenchymal cells. Comparative analysis demonstrated marked similarities of IZ/ACP and GPC organoids to the human embryonic limb, and graft fate and regenerative capacity in vivo were further characterized. We also mimicked the limb skeletal developmental process in a spatially structured manner by vertically positioning two IZ/ACP organoids at both ends of a GPC organoid to generate a human skeletal assembloid. Notably, this human skeletal assembloid recapitulated endochondral ossification with longitudinal skeletal growth upon transplantation. In summary, our study provides a novel research platform for human limb skeletal development and disease.
2025-01-26 | GSE288044 | GEO
Project description:Despite recent advances in pluripotent stem cell-based approaches to induce skeletal cells, recapitulating human limb skeletal development in terms of structure and longitudinally oriented growth remains an unresolved challenge. Here, we report a method to differentiate human pluripotent stem cells into region-specific skeletal organoids harboring GDF5+PRG4+ interzone/articular chondrocyte progenitors (IZ/ACPs) and SP7+ growth plate chondrocytes (GPCs) via PRRX1⁺ limb-bud mesenchymal cells. Comparative analysis demonstrated marked similarities of IZ/ACP and GPC organoids to the human embryonic limb, and graft fate and regenerative capacity in vivo were further characterized. We also mimicked the limb skeletal developmental process in a spatially structured manner by vertically positioning two IZ/ACP organoids at both ends of a GPC organoid to generate a human skeletal assembloid. Notably, this human skeletal assembloid recapitulated endochondral ossification with longitudinal skeletal growth upon transplantation. In summary, our study provides a novel research platform for human limb skeletal development and disease.
2025-01-26 | GSE288046 | GEO
Project description:Urechis unicinctus is a marine benthic invertebrate that relies primarily on humoral immunity in the innate immune system for body defense. In order to clarify the protein compositions of coelomic fluid and investigate its mechanisms of immunization, the proteomic analysis of coelomic fluid supernatant and coelomocytes in U. unicinctus were carried out.
2025-01-16 | PXD059858 |
Project description:Western Australian Museum Marine Invertebrate Mitogenomes - Terpios hoshinota
| PRJNA826711 | ENA
Project description:Symbiont metagenomic assembly from the marine invertebrate Bugula neritina
| PRJNA322176 | ENA