Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Staphylococcus hominis strain:SH08_17

ABSTRACT: Staphylococcus hominis strain:SH08_17 Genome sequencing and assembly

PROVIDER: PRJNA419709 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	PHKL01.dat.gz	Other
	PHKL01.fasta.gz	Fasta.gz
	PHKL01.master.dat	Other
	PHKL01.dat.gz	Other

Items per page:

1 - 4 of 4

Similar Datasets

The ubiquitous human skin commensal Staphylococcus hominis protects against opportunistic pathogens

Project description:Staphylococcus hominis is frequently isolated from human skin and we hypothesize that it may protect the cutaneous barrier from opportunistic pathogens. We determined that S. hominis makes six unique auto inducing peptide (AIP) signals that inhibit the major virulence factor accessory gene regulator (agr) quorum sensing system of Staphylococcus aureus. We solved and confirmed the structures of three novel AIP signals in conditioned media by mass spectrometry, then validated synthetic AIP activity against all S. aureus agr classes. Synthetic AIPs also inhibited the conserved agr system in a related species, Staphylococcus epidermidis. We determined the distribution of S. hominis agr types on healthy human skin and found S. hominis agr-I and agr-II were highly represented across subjects. Further, synthetic AIP-II was protective in vivo against S. aureus-associated dermonecrotic or epicutaneous injury. Together, these findings demonstrate that a ubiquitous colonizer of human skin has a fundamentally protective role against opportunistic damage.

2022-04-04 | GSE199818 | GEO

Staphylococcus hominis subsp. hominis strain:nu4

Project description:Staphylococcus hominis subsp. hominis strain:nu4 Genome sequencing

| PRJNA1051323 | ENA

Staphylococcus hominis strain:ShoR14

Project description:Staphylococcus hominis strain:ShoR14 Genome sequencing and assembly

| PRJNA717998 | ENA

Staphylococcus hominis strain:Hudgins

Project description:Staphylococcus hominis strain:Hudgins Genome sequencing and assembly

| PRJNA327386 | ENA

Staphylococcus hominis strain:SH04_17

Project description:Staphylococcus hominis strain:SH04_17 Genome sequencing and assembly

| PRJNA419707 | ENA

Staphylococcus hominis strain:C34847

Project description:Staphylococcus hominis strain:C34847 Genome sequencing and assembly

| PRJNA313096 | ENA

Staphylococcus hominis strain:G15S1

Project description:Staphylococcus hominis strain:G15S1 Genome sequencing and assembly

| PRJNA955416 | ENA

Staphylococcus hominis strain:MMP2

Project description:Staphylococcus hominis strain:MMP2 Genome sequencing and assembly

| PRJNA304219 | ENA

Staphylococcus hominis strain:SHYJILJH

Project description:Staphylococcus hominis strain:SHYJILJH Genome sequencing and assembly

| PRJNA580115 | ENA

Staphylococcus hominis strain:MBL_AB63

Project description:Staphylococcus hominis strain:MBL_AB63 Genome sequencing and assembly

| PRJNA687181 | ENA

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data