Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

The Transgenerational Effects of Prenatal Synthetic Glucocorticoids on the Prefrontal Cortex

ABSTRACT: The Transgenerational Effects of Prenatal Synthetic Glucocorticoids on the Prefrontal Cortex

PROVIDER: PRJNA420037 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR6326190.fastq.gz	Fastqsanger.gz
	SRR6326200.fastq.gz	Fastqsanger.gz
	SRR6326210.fastq.gz	Fastqsanger.gz
	SRR6326191.fastq.gz	Fastqsanger.gz
	SRR6326201.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 35

Similar Datasets

The Transgenerational Effects of Prenatal Synthetic Glucocorticoids on the Prefrontal Cortex

Project description:First generation animals (F1) were exposed to multiple courses of synthetic glucocorticoids in utero. Animals were then bred to produce second (F2) and third (F3) generation offspring. These animals underwent behavioural assessmenets before sacrifice. In this experiment the prefrontal cortex for F1, F2, and F3 female animals, as well as F1 males (Beta and Control) have been extracted via micro-punch and RNA has been extracted.

2019-02-05 | GSE107415 | GEO

The Transgenerational Effects of Prenatal Synthetic Glucocorticoids on the Hippocampus Cortex

Project description:The Transgenerational Effects of Prenatal Synthetic Glucocorticoids on the Hippocampus Cortex

| PRJNA431992 | ENA

The Transgenerational Effects of Prenatal Synthetic Glucocorticoids on the Hippocampus Cortex

Project description:First generation animals (F1) were exposed to multiple courses of synthetic glucocorticoids in utero. Animals were then bred to produce second (F2) and third (F3) generation offspring. These animals underwent behavioural assessmenets before sacrifice. In this experiment the prefrontal cortex for F1, F2, and F3 female animals, as well as F1 males (Control and sGC) have been extracted via micro-punch and RNA has been extracted.

2020-04-14 | GSE109765 | GEO

Expression data from adult mouse Prefrontal Cortex following prenatal infection

Project description:Prenatal exposure to infectious or inflammatory insults can increase the risk of neuropsychiatric disorders with neurodevelopmental components, including schizophrenia and autism. The molecular processes underlying this pathological association are only partially understood. Here, we implemented an unbiased genome-wide transcriptional profiling of the prefrontal cortex of mice exposed to prenatal infection on GD17 compared to control subjects in order to elucidate the long term molecular signature of late prenatal infection. We used microarray analysis to investigate the long lasting gene expression changes in a well-established mouse model that is based on maternal treatment with the viral mimic poly(I:C) during pregnancy C57BL/6 mice were treated with the synthetic viral mimetic poly(I:C) (5 mg/kg, i.v.) or control (saline, i.v.) solution on gestation day 17. Offspring were subjected to cognitive and behavioral testing in adulthood, and then whole genome gene expression analysis with Affymetrix Microarray and subsequent q-PCR validation were performed on the prefrontal Cortex.

2016-03-01 | E-GEOD-77972 | biostudies-arrayexpress

The Transgenerational Effects of Prenatal Synthetic Glucocorticoids

Project description:First generation animals (F1) were exposed to multiple courses of synthetic glucocorticoids in utero. Animals were then bred to produce second (F2) and third (F3) generation offspring. These animals underwent behavioural assessmenets before sacrifice. In this experiment the paraventricular nucleus of the hypothalamus fo F1, F2, and F3 female anmials (Beta and Control) have been extracted via micro-punch and RNA has been extracted.

2017-11-01 | GSE85822 | GEO

Expression data from adult mouse Prefrontal Cortex following prenatal infection

2016-03-01 | GSE77972 | GEO

Cavia porcellus

Project description:The Transgenerational Effects of Prenatal Synthetic Glucocorticoids

| PRJNA339489 | ENA

DNA methylome signatures of prenatal exposure to synthetic glucocorticoids in hippocampus and peripheral whole blood of female guinea pigs in early life

Project description:We examined the hypothesis that prenatal synthetic glucocorticoids (sGC) administration alters DNA methylation signatures in Guinea pig offspring hippocampus and whole blood. Guinea pigs were treated with sGC or saline in late gestation. Genome-wide modifications of DNA methylation were analyzed using reduced representation bisulfite sequencing in juvenile female offspring.

2020-12-18 | GSE163447 | GEO

Perinatal morphine exposure and the offspring prefrontal cortex

Project description:To investigate how exposure to morphine during the prenatal and early postnatal period affects the offspring prefrontal cortex in a mouse model We performed gene expression profiling analysis using data obtained from RNA-seq of offspring prefrontal cortical brain samples at postnatal day 21

2022-10-26 | GSE206032 | GEO

Comparative phosphoproteomic profiling in prefrontal cortex of prenatal stressed offspring rats

Project description:We used MS-based TMT quantitative proteomics in combination with phosphopeptide enrichment method to compare phosphoproteomic profiling in prefrontal cortex of of PS-S and CON offspring rats.

2022-08-12 | PXD026563 | Pride

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data