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Comparative expression of whole duodenum from intestinal Arx deficient mice and control littermates

ABSTRACT: Comparative expression of whole duodenum from intestinal Arx deficient mice and control littermates

PROVIDER: PRJNA421502 | ENA |

REPOSITORIES: ENA

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Comparative expression of whole duodenum from intestinal Arx deficient mice and control littermates

Project description:The enteroendocrine lineage secretes hormones which direct the digestion, absorption, and motility of the intestine. Arx is a transcription factor expressed specifically in the enteroendocrine cells. With intestinal-specific loss of Arx, hormonal expression is disrupted. We used microarrays to determine the differential expression of genes from the whole duodenum after removal of Arx, a gene specifically expressed in the enteroendocrine lineage, in the intestinal epithelium compared to littermate controls at postnatal day 5.

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