Project description:the purpose of the study is to compare the gene expression profile of WT vs. XBP1 Mutant Drosophila Larvae Methods: RNA sequencing was performed from 2nd instar Larvae of WT and XBP1 Mutant flies Results: Across the 4 samples, there was an average of 51 million mapped reads per sample with an average unique mapping rate of 83%. Using an adjusted p-value cutoff of 0.05, 154 genes were calculated to be differentially expressed. Conclusions: XBP1 affects gene expression profiling in drosophila larvae
Project description:Gene expression profiles in lri12 mutant zebrafish larvae at 5 dpf based on RNAseq data. This dataset was also used to clone the mutation.
Project description:We generated a 16 nucleotide deletion mutant in the zebrafish fbln1 gene and we compared the whole larvae transcriptome to wt siblings in 10dpf larvae.
Project description:We identified Gyc76C as a novel regulator in Drosophila innate immunity We used microarray to examine gene expression in Gyc76C mutant lines.