Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Single Cell RNA-Seq profiling human embryonic kidney cortex cells

ABSTRACT: Single Cell RNA-Seq profiling human embryonic kidney cortex cells

PROVIDER: PRJNA448195 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Single Cell RNA-Seq profiling human embryonic kidney cortex cells [H14w]

Project description:Single Cell RNA-Seq profiling human embryonic kidney cortex cells [H14w]

| PRJNA579085 | ENA

Single Cell RNA-Seq profiling human embryonic kidney cortex cells

Project description:To characterize the cellular diversity in the human kidney cortical nephrogenic niche we dissociated cells from the cortex and performed 10X Genomics single-cell RNA sequencing.

2018-02-14 | GSE102596 | GEO

Single Cell RNA-Seq profiling human embryonic kidney cortex cells

2018-04-13 | GSE112570 | GEO

Single Cell RNA-Seq profiling human embryonic kidney cortex cells [H14w]

2020-04-01 | GSE139280 | GEO

Single Cell RNA-Seq profiling of human embryonic kidney outer and inner cortical cells and kidney organoid cells

Project description:To study the developmental process of human podocytes and compare to the in vitro counterpart, we dissociated cells from the inner and outer kidney cortex as well as kidney organoids, and performed 10X Genomics single-cell RNA sequencing.

2019-06-19 | GSE124472 | GEO

Genome-wide map of SIX2 and SIX1 binding in human embryonic kidney cortex

Project description:Genome-wide map of SIX2 and SIX1 binding in human embryonic kidney cortex

| PRJNA298244 | ENA

microRNA profiling from kidney cortex samples of Macaca fascicularis (Cynomolgus Monkey)

Project description:MicroRNAs (miRNAs) present in tissues and biofluids are emerging as sensitive and specific safety biomarkers. MiRNAs have not been thoroughly described in M. fascicularis, an animal model used in pharmaceutical industry especially in drug safety evaluation. Here we investigated the miRNAs in M. fascicularis. For Macaca mulatta, a closely related species of M.fascicularis, 619 stem-loop precursor miRNAs (pre-miRNAs) and 914 mature miRNAs are available in miRBase version 21. Using M. mulatta miRNAs as a reference list and homology search tools, we identified 604 pre-miRNAs and 913 mature miRNAs in the genome of M.fascicularis. In order to validate the miRNAs identified by homology search we attempted to sequence miRNAs expressed in kidney cortex from M. fascicularis. MiRNAs expressed in kidney cortex may indeed be released in urine upon kidney cortex damage and be potentially used to monitor drug induced kidney injury. Hence small RNA sequencing libraries were prepared using kidney cortex tissues obtained from three naive M. fascicularis and sequenced. Analysis of sequencing data indicated that 432 out of 913 mature miRNAs were expressed in kidney cortex tissues. Assigning these 432 miRNAs to pre-miRNAs revealed that 273 were expressed from both the -5p and -3p arms of 150 pre-miRNAs and 159 miRNAs expressed from either the -5p or -3p arm of 176 pre-miRNAs. Mapping sequencing reads to pre-miRNAs also facilitated the detection of twenty-two new miRNAs. To substantiate miRNAs identified by small RNA sequencing, 313 miRNAs were examined by RT-qPCR. Expression of 262 miRNAs in kidney cortex tissues ware confirmed by TaqMan microRNA RT-qPCR assays. Analysis of kidney cortex miRNA targeted genes suggested that they play important role in kidney development and function. Data presented in this study may serve as a valuable resource to assess the renal safety biomarker potential of miRNAs in Cynomolgus monkeys.

2016-09-13 | GSE86836 | GEO

Single-Cell Transcriptomes of Cerebral Cortex in Embryonic 18 Days

Project description:Single-Cell Transcriptomes of Cerebral Cortex in Embryonic 18 Days

| PRJNA507356 | ENA

Single-Cell Transcriptomes of Cerebral Cortex in Embryonic 18 Days

Project description:Cajal-Retzius cells have important role in cerebral cortex development, such as secreted Reln protein, maintain normal lays of cerebral cortex. To explore novel secretory protein of Cajal-Retzius cells and to survey the roles of Cajal-Retzius cells in cerebral cortex development, we analyzed transcriptome profiles of 6753 single cells of the embryonic 18 days.

2019-11-27 | GSE123035 | GEO

RNA-seq of human kidney cortex and medulla

Project description:We report gene expression (RNA-seq) from macro-dissected human kidney cortex and medulla from 3 individuals

2023-11-22 | GSE212907 | GEO