Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Host-pathogen transcriptomics of Mucor circinelloides spores phagocytosed by mouse macrophages

ABSTRACT: Host-pathogen transcriptomics of Mucor circinelloides spores phagocytosed by mouse macrophages

PROVIDER: PRJNA481961 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR7541440.fastq.gz	Fastqsanger.gz
	SRR7541450.fastq.gz	Fastqsanger.gz
	SRR7541441.fastq.gz	Fastqsanger.gz
	SRR7541451.fastq.gz	Fastqsanger.gz
	SRR7541442.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 24

Similar Datasets

Host-pathogen transcriptomics of Mucor circinelloides spores phagocytosed by mouse macrophages

Project description:Here, we have studied the first stage of this infection—the interaction of Mucor circinelloides spores with phagocytic cells—from an integrated transcriptomic and functional perspective. Our transcriptomic results showed that a relevant gene network is remodelled in response to phagocytosis, enriched in crucial functions to survive the phagosome, such as nutritional adaptation and response to oxidative stress. An additional transcriptomic analysis of atf1 and atf2 mutants unveiled the complex gene network of secondarily regulated genes involved in the response to phagocytosis. These new insights into the initial phase of mucormycosis define genetic regulators and molecular processes that could serve as pharmacological targets.

2019-01-09 | GSE117385 | GEO

Host-pathogen transcriptomics of Mucor circinelloides NCRIP deficient spores phagocytosed by mouse macrophages

Project description:Host-pathogen transcriptomics of Mucor circinelloides NCRIP deficient spores phagocytosed by mouse macrophages

| PRJNA597352 | ENA

ChIP-seq with Mucor circinelloides Mis12- and Dsn1-mCherry proteins

Project description:ChIP-seq experiment with two outer kinetochore proteins to identify the centromeric sequences of Mucor circinelloides

2019-10-09 | GSE132687 | GEO

Endogenous short RNAs in Mucor circinelloides sequenced on the Illumina platform (Solexa)

Project description:We sequenced Endogenous short RNAs in Mucor circinelloides fungus grown in standard liquid culture. Short RNAs were profiled in wild type, Dicer-like 1 mutant (dcl1-), Dicer-like 2 mutant (dcl2-) and double Dicer mutant (dcl1-/dcl2-) strains. We identified many loci that produced less short RNAs in the dcl2- strain suggesting that DCL2 is the major protein generating short RNAs in Mucor circinelloides.

2010-04-28 | GSE18958 | GEO

Endogenous short RNAs in Mucor circinelloides sequenced on the Illumina platform (Solexa)

2010-04-28 | E-GEOD-18958 | biostudies-arrayexpress

Regulation of gene expression by light in the fungus Mucor circinelloides

Project description:Transcriptional profiling of wild-type strain (R7B) of the fungus Mucor circinelloides comparing control mycelia grown for 18 hours in the dark with mycelia grown in the same conditions and illuminated with white light for 20 min. Goal was to identify genes regulated by a pulse of white light.

2016-06-06 | GSE58264 | GEO

Mucor circinelloides

Project description:Mucor circinelloides Genome sequencing

| PRJNA1024405 | ENA

Host-pathogen transcriptomics of Mucor circinelloides NCRIP deficient spores phagocytosed by mouse macrophages

Project description:Here in this work, we uncovered the role of NCRIP in regulating virulent processes and transposable movements through key components of the pathway, RdRP1 and R3B2. Mutants in these genes are unable to launch a proper virulent response to macrophage phagocytosis, resulting in a decreased virulence potential. The transcriptomic profile of rdrp1Δ and r3b2Δ mutants revealed a pre-exposure adaptation to the stressful phagosomal environment even when the strains are not confronted by macrophages.

2020-06-11 | GSE142543 | GEO

Mucor circinelloides

Project description:Mucor circinelloides Small RNA sequencing

| PRJNA200295 | ENA

Mucor circinelloides

Project description:NBRP: Genome sequencing of Mucor circinelloides JCM 22480

| PRJDB3642 | ENA