Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Metagenomic Study of the Caprid Rumen Virome

PROVIDER: PRJNA485606 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR7686970.fastq.gz	Fastqsanger.gz
	SRR7686971.fastq.gz	Fastqsanger.gz

Items per page:

1 - 2 of 2

Similar Datasets

Metagenome and Viral Interrogation of a Moose Rumen Microbial Community

Project description:Proteomic data from moose fistulated rumen; metagenomic and viral sequencing performed; metabolic pathways reconstructed

2018-07-03 | PXD008667 | Pride

TEST

Project description:WORKSHOP METAGENOMIC RUMEN STUDY

| PRJEB12660 | ENA

bovine gut metagenome

Project description:RUMEN STUDY metagenomic assembly

| PRJNA292370 | ENA

Rumen Virome metagenomics

Project description:Rumen Virome metagenome sequencing

| PRJEB9170 | ENA

The unexpected role of HBx in UC

Project description:Ulcerative colitis is a chronic inflammatory disorder for which a definitive cure is still missing. This is characterized by an overwhelming inflammatory milieu in the colonic tract where a composite set of immune and non-immune cells orchestrate its pathogenesis. Over the last years, a growing body of evidence has been pinpointing gut virome dysbiosis as underlying its progression. Nonetheless, its role during the early phases of chronic inflammation is far from being fully defined. Here we show the gut virome-associated Hepatitis B virus protein X, most likely acquired after an event of zoonotic spillover, to be associated with the early stages of ulcerative colitis and to induce colonic inflammation in mice. It acts as a transcriptional regulator in epithelial cells, provoking barrier leakage and altering mucosal immunity at the level of both innate and adaptive immunity. This study paves the way to the comprehension of the aetiopathogenesis of intestinal inflammation and encourages further investigations of the virome as a trigger also in other scenarios. Moreover, it provides a brand-new standpoint that looks at the virome as a target for tailored treatments, blocking the early phases of chronic inflammation and possibly leading to better disease management.

2023-02-20 | GSE204665 | GEO

Detection of carbohydrate-active enzyme genes in the rumen of young lambs

Project description:In this study, we studied the fibrolytic potential of the rumen microbiota in the rumen of 6 lambs separated from their dams from 12h of age and artificially fed with milk replacer (MR) and starter feed from d8, in absence (3 lambs) or presence (3 lambs) of a combination of the live yeast Saccharomyces cerevisiae CNCM I-1077 and selected yeast metabolites. The fibrolytic potential of the rumen microbiota of the lambs at 56 days of age was analyzed with a DNA microarray (FibroChip) targeting genes coding for 8 glycoside hydrolase (GH) families.

2019-10-01 | GSE122256 | GEO

Project description:Apple virome study

| PRJNA1115969 | ENA

Project description:Apple virome study

| PRJNA898441 | ENA

The mechanism of promoting proliferation of rumen epithelial cells in Tan sheep by adding succinate to the diet based on the interaction between rumen microbiota and host.

Project description:A healthy rumen is crucial for normal growth and improved production performance of ruminant animals. Rumen microbes participate in and regulate rumen epithelial function, and the diverse metabolites produced by rumen microbes are important participants in rumen microbe-host interactions. SCFAs, as metabolites of rumen microbes, have been widely studied, and propionate and butyrate have been proven to promote rumen epithelial cell proliferation. Succinate, as an intermediate metabolite in the citric acid cycle, is a final product in the metabolism of certain rumen microbes, and is also an intermediate product in the microbial synthesis pathway of propionate. However, its effect on rumen microbes and rumen epithelial function has not been studied. It is unclear whether succinate can stimulate rumen epithelial development. Therefore, in this experiment, Chinese Tan sheep were used as experimental animals to conduct a comprehensive analysis of the rumen microbiota community structure and rumen epithelial transcriptome, to explore the role of adding succinate to the diet in the interaction between the rumen microbiota and host.

2023-06-12 | GSE233696 | GEO

Rumen fluid miRNAome of dry cows transitioned from forage to 65% grain diet

Project description:This study aimed to explore the changes in miRNAome in the rumen fluid during diet transition from forage to high-grain.

2022-02-03 | GSE195757 | GEO