Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Whole transcriptome analysis in 661W photoreceptor cells

ABSTRACT: Whole transcriptome analysis in 661W photoreceptor cells

PROVIDER: PRJNA488424 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR7765320.fastq.gz	Fastqsanger.gz
	SRR7765330.fastq.gz	Fastqsanger.gz
	SRR7765340.fastq.gz	Fastqsanger.gz
	SRR7765321.fastq.gz	Fastqsanger.gz
	SRR7765331.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 24

Similar Datasets

Whole transcriptome analysis in 661W photoreceptor cells

Project description:This experiment aimed to characterise the complete transcriptional profile of 661W cells to identify their origin as cone photoreceptor cells. Cells were either grown in complete media or subjected to 72 hours of serum starvation to encourage differentiation.

2018-08-30 | GSE119190 | GEO

Intestinal Microbiome, Oral Microbiome, and Whole Blood Transcriptome Analyses in Gastrointestinal Malignancies

Project description:The primary objective of this prospective observational study is to characterize the gut and oral microbiome as well as the whole blood transcriptome in gastrointestinal cancer patients and correlate these findings with cancer type, treatment efficacy and toxicity. Participants will be recruited from existing clinical sites only, no additional clinical sites are needed.

| 2742033 | ecrin-mdr-crc

Transcriptome profiling of developing photoreceptor subtypes reveals candidate genes for avian photoreceptor diversification

Project description:Purpose: Avian photoreceptors are a diverse class of neurons, comprised of four single cones, the two members of the double cone, and rods. Many distinctive features of photoreceptor subtypes, including spectral tuning, oil droplet size and pigmentation, synaptic targets and spatial patterning, have been well characterized, but the molecular mechanisms underlying these attributes have not been explored. Furthermore, the signaling events and transcriptional regulators driving the differentiation of these diverse photoreceptors are currently unknown. Methods: To identify genes specifically expressed in distinct chicken (Gallus gallus) photoreceptor subtypes, we developed fluorescent reporters that label photoreceptor subpopulations, isolated these subpopulations using fluorescence-activated cell sorting, subjected them to next-generation sequencing, and conducted differential expression analysis. Results: We identified hundreds of differentially expressed genes from photoreceptor subpopulations labeled with rhodopsin, red opsin, green opsin, and violet opsin reporters. These genes are involved in a variety of processes, including phototransduction, transcriptional regulation, cell adhesion, maintenance of intra- and extra-cellular structure, and metabolism. Of particular note are a variety of differentially expressed transcription factors, which may drive and maintain photoreceptor diversity, and cell adhesion molecules that may mediate spatial patterning of photoreceptors and act to establish retinal circuitry. Conclusions: These analyses provide a framework for future studies that will dissect the role of these various factors in the differentiation of avian photoreceptor subtypes. mRNA expression profiling of 5 pairs of photoreceptor subtypes isolated from chicken retinal explants, 3 replicates per sample

2014-09-01 | E-GEOD-59850 | biostudies-arrayexpress

Whole Transcriptome analysis of Aurintricarboxylic acid treated NIH3T3 cells

Project description:Whole Transcriptome analysis of Aurintricarboxylic acid treated NIH3T3 cells

| PRJNA813624 | ENA

RNA-seq analysis the whole transcriptome in MCF7 cells

Project description:RNA-seq analysis the whole transcriptome in MCF7 cells

| PRJNA616265 | ENA

Analysis of gene expression profile in photoreceptor-like cells derived from fibroblasts

Project description:To clarify disease-specific profiles, we employed DNA microarray analysis using induced photoreceptor-like cells derived from fibroblasts.

2022-04-04 | GSE199050 | GEO

Gene expression analysis of embryonic photoreceptor precursor cells using BAC-Crx-EGFP transgenic mouse.

Project description:We generated a transgenic mouse line which express EGFP in the retina driven by the Crx promoter using BAC transgenesis. We sorted EGFP-positive photoreceptor precursors at E17.5 using FACS, and subsequently performed microarray analysis of the FACS-sorted cells. In order to clarify a molecular role of Crx in developing cone photoreceptor precursors, we investigated the expression profile of the BAC-Crx-EGFP-positive cells compared with that of the BAC-Crx-EGFP-negative cells at E17.5.

2010-12-25 | E-GEOD-25607 | biostudies-arrayexpress

Transcriptome profiling of developing photoreceptor subtypes reveals candidate genes for avian photoreceptor diversification

2014-09-01 | GSE59850 | GEO

Whole transcriptome analysis of mucosal melanoma

Project description:Whole transcriptome analysis of mucosal melanoma

| PRJNA847677 | ENA

Whole transcriptome analysis of mucosal melanoma

Project description:Whole transcriptome analysis of mucosal melanoma

| PRJNA847678 | ENA