RNAseq on developmental endoreplicating (salivary glands) cells in Drosophila melanogaster
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ABSTRACT:
PROVIDER: PRJNA501887 | ENA |
REPOSITORIES: ENA
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Project description:In order to evaluate the global transcriptomic changes in endoreplicating cells in Drosophila melanogaster we performed RNA-Seq. Endoreplicating cells (salivary glands) and mitotic cycling cells (brains and imaginal discs) were harvested from feeding 3rd instar larvae and mRNA levels were compared. Consistent with our previous results, we found that endoreplicating cells repress genes regulated by the E2F1 transcription factor as well as genes regulated by the Myb-MuvB (MMB) transcription factor complex.
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Project description:ChiP-seq profiling of Drosophila melanogaster salivary glands to identify targets for NSL1 and MCRS2. ArrayExpress Release Date: 2010-04-16 Publication Title: The Nonspecific Lethal Complex Is a Transcriptional Regulator in Drosophila Publication Author List: Raja SJ, Charapitsa I, Conrad T, Vaquerizas JM, Gebhardt P, Holz H, Kadlec J, Fraterman S, Luscombe NM, Akhtar A. Person Roles: submitter Person Last Name: Vaquerizas Person First Name: Juan Person Mid Initials: M Person Email: jvaquerizas@ebi.ac.uk Person Phone: Person Address: Person Affiliation: EBI
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