Project description:Characteristics of the gut microbiome in esports players compared with those in physical education students and professional athletes
Project description:Probiotics may alter stress sensitivity by modulating the gut-brain axis. The heat-inactivated, enteric-colonizing Lactobacillus gasseri, CP2305 (paraprobiotic CP2305), has been shown to ameliorate psychological stress-related symptoms. This study was designed to reveal the beneficial effects of paraprobiotic CP2305 on top athletes experiencing physical and mental stresses.
Project description:Association of gut microbiota and gut metabolites and adverse outcomes in Biliary Atresia - a longitudinal prospective cohort controlled study
Project description:Endurance-trained athletes have high oxidative capacity, enhanced insulin sensitivity, and high intracellular lipid accumulation in muscle. These characteristics are likely due to altered gene expression levels in muscle. We used microarrays to detect gene expression profile in endurance-trained athlete skeletal muscle.
Project description:Thirteen elite handball athletes and 13 sedentary controls. Three timepoints were established: T0 (baseline conditions); T8 (after 8 weeks of supplementation); and T16 (after 8 weeks in the absence of supplementation). The dietary intervention consisted of the oral administration of one daily multivitamin/mineral complex capsule (Multicentrum® Pfizer, Barcelona, Spain) before exercise during the controlled dietary intervention period. Multivitamin/mineral complex intervention adherence/compliance was defined as the percentage of all of the supplement capsules ingested throughout the study period. The expressions of a total 112 of genes were evaluated by RT-qPCR analysis with the QuantStudioTM 12K Flex Real-Time PCR System. 78 genes were finally analized.
Project description:We have previously demonstrated (Calura E et al., 2013) that different epithelial ovarian cancer (EOC) histotypes have different, defined characteristics at the microRNA level, which might highlight a different originating tissue for the disease. From these results we have invesigated whole-genome gene expression on a cohort of samples with different FIGO grades, in order to investigate the link between the tumor grade and gene expression.
