Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Homo sapiens

ABSTRACT: Homo sapiens TCR-seq Raw sequence reads on Graves’ ophthalmopathy disease

PROVIDER: PRJNA516296 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR8491820_1.fastq.gz	Fastqsanger.gz
	SRR8491820_2.fastq.gz	Fastqsanger.gz
	SRR8491830_1.fastq.gz	Fastqsanger.gz
	SRR8491830_2.fastq.gz	Fastqsanger.gz
	SRR8491840_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 269

Similar Datasets

Homo sapiens

Project description:Homo sapiens TCR repertoire sequencing Raw sequence reads on Graves’ ophthalmopathy disease

| PRJNA516279 | ENA

Homo sapiens

Project description:TCR repertoire sequencing on Graves’ ophthalmopathy disease

| PRJNA449605 | ENA

The cardiac calsequestrin gene (CASQ2) is up-regulated in the thyroid in patients with Graves’ ophthalmopathy

Project description:Thyroid-associated ophthalmopathy (TAO) is a complex eye and orbital disorder that is uniquely linked to Graves’ hyperthyroidism (GH). A popular explanation for the development of orbital inflammation in these patients is autoimmunity against the TSH-receptor expressed in orbital preadipocytes. However, this has not been proven and alternative hypotheses should be entertained. We have shown recently that antibodies against highly purified rabbit skeletal muscle calsequestrin are sensitive and specific markers of eye muscle inflammation in patients with thyroid autoimmunity. Keywords: disease state comparison In the study presented here, RNA from thyroid tissue of hyperthyroid patients with (n=10) and without (n=8) symptoms of ophthalmopathy was compared across 20,589 genes.

2007-10-16 | E-GEOD-9340 | biostudies-arrayexpress

LncRNA ENST00000581911 regulates extraocular muscle remodeling by interacting with KHSRP in Graves’ ophthalmopathy

Project description:To reveal the potential role of lncRNAs in the extraocular muscles (EOMs) of Graves' ophthalmopathy (GO), we performed lncRNA expression profiling and compared their expression differences between EOM tissues sampled from GO and concomitant esotropia (CET) patients using microarray analysis. To reveal the potential role of lncRNAs in the extraocular muscles (EOMs) of Graves' ophthalmopathy (GO), we performed lncRNA expression profiling and compared their expression differences between EOM tissues sampled from GO and concomitant esotropia (CET) patients using microarray analysis.

2024-10-12 | GSE278934 | GEO

Morus alba Raw protein sequence reads

Project description:Morus alba L. Raw protein sequence reads and sequence

2024-02-08 | PXD049451 |

Affymetrix SNP array data for pharmacogenomic profile of Benzidazole adverse reactions.

Project description:Search for SNPs associated with the pharmacogenomic profile of Benzidazole adverse reactions in Chagas Disease Homo sapiens patients.

2021-03-31 | GSE154421 | GEO

RNA-Seq of retinal tissue from a Human Eye

Project description:We report RNA-Seq experiments of retinal tissue from Homo Sapiens

2016-09-12 | GSE84930 | GEO

The prevalence of human cytomegalovirus in colorectal cancer and viral gene expression profiles

Project description:Five HCMV (+) CRC tissues detected by PCR were selected for RNA-seq. GEPs were pre-processed by Cutadapter and FastQC to remove jointed reads and low-quality reads. Tophat (v.2.0.0) was used to compare the sequences with Homo sapiens and HCMV genomes. The GEPs of HCMV was determined by Integrated Genomics Viewer (IGV) and Partek® Genomics Suite™ (version 6.5 beta, Partek Inc., St. Louis, MO, USA).

2021-04-30 | GSE173609 | GEO

Rett syndrome-causing MECP2 mutations severely impact key cellular and molecular features of human astrocytes

Project description:Purpose: The goal of this RNA sequencing (RNA-seq) study is to identify aberrations in the astrocyte transcriptional landscape caused by R270X mutation in MECP2. Methods: mRNA-seq analysis was performed on total RNA extracted from human embryonic stem cell (ESCs)-derived wild-type (WT) and MECP2-R270X mutant astrocytes. The R270X mutation was inserted into ESCs (line H1) via CRISPR/Cas9 technology. Samples were generated in triplicates, sequenced by Illumina NovaSeq 6000 Sequencing System. Raw reads were first trimmed for 10 bases at the 5’end to remove reads with biased nucleotide (ACGT) distribution. Trimmed reads were then aligned to the Homo sapiens genome (GRCh38p12, GENCODE, primary assembly), using STAR aligner. Differential gene expression (DEG) analyses on the read counts were performed using DESeq2. Genes with sum of read counts across all samples with less 10 were filtered out from analysis. Results: Our RNA-seq analysis showed that 1,621 genes were dysregulated in mutant astrocytes (fold-change >1.5 or <2/3; padj < 0.05, average reads count >10 in at least one genotype)

2024-02-15 | GSE185726 | GEO

Transcription profiling by array of lymphocytes form post-menopausal women after consuming de-alcoholized red wine with low or high proanthocyanidin concentrations

Project description:Experiment with 32 hybridizations, using 16 samples of species [Homo sapiens], using 32 arrays of array design [Affymetrix Custom Array - NuGO_Hs1a520180], producing 32 raw data files and 1 transformed and/or normalized data files.

2010-07-20 | E-MEXP-2616 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data