Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Molecular tools for implementing international ballast water regulations – insights and reflections from a cross-latitudinal en-route study

PROVIDER: PRJNA526939 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR8727860_1.fastq.gz	Fastqsanger.gz
	SRR8727860_2.fastq.gz	Fastqsanger.gz
	SRR8727870_1.fastq.gz	Fastqsanger.gz
	SRR8727870_2.fastq.gz	Fastqsanger.gz
	SRR8727880_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 384

Similar Datasets

Metabarcoding study of ballast water onboard RV "Polarstern" - first day DNA samples, 3 fractions

Project description:En-route metabarcoding study of ballast water - comparative study of ballast water assessment using molecular apporaches (eDNA/eRNA metabarcoding and ATP tests)

| PRJEB25035 | ENA

Differential transcript stability measurements in MDA-MB-231 vs. MDA-LM2 cells

2014-07-24 | GSE49608 | GEO

Rational targeting of dynamic tumor subclones in relapsing human glioblastoma

Project description:Glioblastoma therapy relies on the alkylating drug temozolomide (TMZ) administered to irradiated patients post-neurosurgery, which increases overall survival but cannot prevent fatal disease relapse. Using clinical samples and glioblastoma models, we here identify TMZ-driven enrichment of ALDH1A1+ tumor subclones acquiring AKT-dependent drug resistance en route to relapse. We demonstrate that this recurrent phenotype switch is predictable and can be countered by a sequential rather than simultaneous combinatorial treatment approach.

2020-02-12 | GSE145128 | GEO

Differential transcript stability measurements in MDA-MB-231 vs. MDA-LM2 cells

Project description:We performed whole-genome stability measurements for MDA-MB-231 and its highly metastatic derivative MDA-LM2. Our goal was to identify post-transcriptonal regulons that are deregulated en route to higher metastatic capacity. Cells were pulsed with 4-thiouridine for 2 hours and then RNA was extracted at 0, 2, 4, and 7 hr time-points in quadruplicate from each cell line. 4sU labeling followed by RNA-seq was then used to measure the abundance of transcripts in each population. A decay rate was estimated based on the rate at which transcript abundance was reduced at these time-points.

2014-07-24 | E-GEOD-49608 | biostudies-arrayexpress

ATAC-seq on ESCs undergoing directed differentiation towards defined neural fates

Project description:We have used ATAC-seq to track cell state changes that occur during the differentiation of mouse embryonic stem cells to defined neural progenitor fates. We have performed ATAC-seq every 24 hours in cells en route to 3 distinct neural progenitors fates, anterior, hindbrain and spinal cord. This has allowed us to define how cells transition to a neural state, based on their enhancer usage. We identified regions distinct to different anterior-posterior neural progenitors, and validated their relevance by performing in vivo ATAC-seq on neural progenitors isolated from different axial levels of mouse embryos.

2018-08-27 | E-MTAB-6337 | biostudies-arrayexpress

Latitudinal expression analysis of Mytilus californianus

Project description:Transcriptional analysis of the effects of natural environmental variation across the latitudinal range of Mytilus californianus Keywords: Environmental response

2008-03-26 | GSE8935 | GEO

Antagonistic action of PHYA and PHYB is involved in FR-dependent leaf senescence in Arabidopsis accessions

Project description:Sensing environmental changes is important for survival of plants, as sessile organisms, in habi-tat. Recently, latitudinal clines in leaf senescence have been reported to be influenced by tem-perature and photoperiod. However, the relationship of light quality with latitudinal response of leaf senescence is still unclear. Here, we found that Arabidopsis accessions in far-red (FR) showed a strong negative correlation of leaf senescence with the latitude of their origin. phyto-chrome A (phyA) and B (phyB) mutants showed early and delayed senescence in FR, respec-tively, suggesting that PHYA and PHYB are involved in FR-dependent leaf senescence. Tran-scriptomic analysis identified genes oppositely regulated by PHYA and PHYB, and they were mainly associated with phytohormone, temperature, and defense, suggesting their associations with FR-dependent antagonistic effects of PHYA and PHYB on leaf senescence. Among these genes, the expression of WRKY6 in Arabidopsis accessions showed the highest correlation with latitude of their origin. Consistently, wrky6 mutant exhibited delayed senescence phenotype in FR. In conclusion, we propose that PHYs-regulated genes, including WRKY6, are involved in latitudinal leaf senescence in FR and this regulatory mode may contribute to latitudinal adapta-tion by responding FR, as a piece of geographical information.

2018-09-30 | GSE103946 | GEO

Project description:Applying cross-scale regulations to Sedum plumbizincicola and revealing by transcription

| PRJNA1134411 | ENA

human gut metagenome

Project description:A prospective, longitudinal analysis of the developing gut microbiome in infants en route to type 1 diabetes

| PRJNA231909 | ENA

Engineering a new-to-nature cascade for phosphate-dependent formate to formaldehyde conversion in vitro and in vivo

Project description:To realize a carbon-neutral bioeconomy, the concept of electrobiocatalysis has been developed, in which CO2 is first chemically reduced to formate and subsequently assimilated by enzymatic cascades or engineered microbes. A key step in the assimilation of formate is its reduction into formaldehyde, which is chemically challenging. Here, we developed a two-enzyme route in which formate is activated into formyl phosphate and reduced by NAD(P)H into formaldehyde. Exploiting the promiscuity of acetate kinase and N-acetyl--glutamyl phosphate reductase, we demonstrate the phosphate (Pi) route in vitro and in vivo. We further engineered a formyl phosphate reductase variant with improved formyl phosphate conversion in vivo by suppressing cross-talk with native metabolism. We further show that the Pi route can be interfaced with a recently developed formaldehyde assimilation pathway (FORCE pathway) to provide a thermodynamically and kinetically highly efficient route from formate into C2-compounds.

2023-03-22 | MSV000091532 | MassIVE

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data