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Transcriptome sequencing of purified dermal adipocytes and inguinal adipocytes

ABSTRACT: Transcriptome sequencing of purified dermal adipocytes and inguinal adipocytes

PROVIDER: PRJNA528632 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR8769831.fastq.gz	Fastqsanger.gz
	SRR8769832.fastq.gz	Fastqsanger.gz
	SRR8769833.fastq.gz	Fastqsanger.gz
	SRR8769834.fastq.gz	Fastqsanger.gz

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Transcriptome sequencing of purified dermal adipocytes and inguinal adipocytes

Project description:Purpose: The goals of this study are to compare the transcription difference between purified dermal adipocytes and inguinal adipocytes Methods: Transcriptome of purified dermal adipocytes and inguinal adipocytes were generated by deep sequencing, using Illumina Hiseq 2500 v3 sequencing system.

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Transcriptome sequencing of purified dermal adipocytes harvested from P21, P25, P29, P35 and P49 mice

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Project description:Tryptophan-kynurenine metabolism plays an important role in the pathogenesis of several psychiatric diseases but its physiological function in peripheral tissues remains unclear. Physical exercise training activates a biochemical pathway in skeletal muscle that protects from neuroinflammation and, as a byproduct, leads to kynurenic acid accumulation in the periphery. We therefore investigated the effects of kynurenic acid in murine white adipose tissue. We used microarrays to detail global programme of gene expression underlying Kynurenic acid mediated effects on inguinal primary adipocytes.

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