Project description:The data presented is intended to analyse the changes in the expression profiles of human MSCs (Mesenchymal Stromal/Stem Cells) associated to different tissue specific stimulus.
Project description:Cellular therapy is proposed for tendinopathy treatment. Bone marrow- (BM-MSC) and adipose tissue- (ASC-) derived mesenchymal stromal cells are candidate populations for such a therapy. We used microarrays to evaluate the basal gene expression in human BM-MSCs and ASCs and to create list of differentially expressed genes between analyzed groups.
Project description:The data presented is intended to analyse the changes in the expression profiles of human MSCs (Mesenchymal Stromal/Stem Cells) associated to different tissue specific stimulus. Human BM-, PL-, and AD- MSCs, and skin fibroblasts from healthy independent donors were isolated and expanded in vitro. Hematopoietic progenitors and stem cells (HSCs) were isolated applying CD34+ immunomagnetic selection.
Project description:This SuperSeries is composed of the following subset Series: GSE30064: Cultured human amniotic fluid-derived mesenchymal stromal cells [PIQOR data] GSE30065: Cultured human amniotic fluid-derived mesenchymal stromal cells [miRXplore data] Refer to individual Series
Project description:Human mesenchymal stromal cells (MSCs) were treated with TLR3 ligand. LS-MS/MS analysis was performed to reveal changes in proteins related to the immunosuppressive properties of MSCs and to better understand the mechanisms underlying the activation of these properties.