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Analysis of ARID3A and ARID3B regulated genes by RNA-seq

ABSTRACT: Analysis of ARID3A and ARID3B regulated genes by RNA-seq

PROVIDER: PRJNA529973 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR8816610_1.fastq.gz	Fastqsanger.gz
	SRR8816610_2.fastq.gz	Fastqsanger.gz
	SRR8816620_1.fastq.gz	Fastqsanger.gz
	SRR8816620_2.fastq.gz	Fastqsanger.gz
	SRR8816611_1.fastq.gz	Fastqsanger.gz

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Analysis of ARID3A and ARID3B regulated genes by RNA-seq

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Project description:This study employs RNA-seq to investigate the transcriptional effects of Arid3a in Vascular Smooth Muscle Cells (VSMCs), revealing a comprehensive signature of gene expression. We identified 394 genes that were downregulated and 227 that were upregulated in response to Arid3a knockdown, shedding light on its regulatory network. The RNA-seq data highlighted the key role of Arid3a in controlling the dynamics of actin filaments, which has implications for processes such as cell adhesion and the cAMP signaling pathway.

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