Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Genes regulated by SMAD3 in HCC cells

ABSTRACT: Genes regulated by SMAD3 in HCC cells

PROVIDER: PRJNA548278 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Genes regulated by SMAD3 in HCC cells

Project description:To identify genes regulated by SMAD3, we have employed whole transcriptome microarray expression profiling to identify genes downstream of SMAD3. Total RNAs from SMAD3-overexpression (7721-SMAD3 vs 7721-VEC) or SMAD3-knockdown (LM3-shSMAD3 vs LM3-CON) cell lines were measured.

2022-06-10 | GSE132518 | GEO

METTL3 regulated genes in HCC cell

Project description:METTL3 regulated genes in HCC cell

| PRJNA632566 | ENA

Investigation of downstream genes regulated by ACOT12 in HCC cells

Project description:Investigation of downstream genes regulated by ACOT12 in HCC cells

| PRJNA438207 | ENA

Investigation of downstream genes regulated by ACOT12 in HCC cells [MHCC97H]

Project description:Investigation of downstream genes regulated by ACOT12 in HCC cells [MHCC97H]

| PRJNA438078 | ENA

Investigation of downstream genes regulated by ACOT12 in HCC cells [Huh7]

Project description:Investigation of downstream genes regulated by ACOT12 in HCC cells [Huh7]

| PRJNA438077 | ENA

Transcriptomic analysis of the RPS3-regulated genes in HCC cell line

Project description:Transcriptomic analysis of the RPS3-regulated genes in HCC cell line

| PRJNA484691 | ENA

SMAD3 and SOX4 binding profiling in human breast cell lines

Project description:In order to identify genes co-bound by SOX4 and SMAD3 in the context of breast cancer, different breast cell lines (HMLEs, MDA-MB-231 or HCC-1954) were used. Due to low endogenous expression levels for SOX4 in HMLEs in untreated conditions, doxycycline-dependent SOX4 overexpression was obtained by transducing HMLE cells with pIINDUCER21-SOX4 vector..Cells were plated and SOX4 and SMAD3 chromatine-immunoprecipitation was performed in untreated conditions, TGF-beta (2.5ng/ml), doxycycline (0.5ug/ml) or both as indicated. Genome-wide binding sites for SOX4 and SMAD3 was identified in HMLEs, MAD-MB-231 and HCC-1954 cells.

2018-06-11 | GSE104760 | GEO

Nrf2 regulated genes in A549 cells

Project description:Nrf2 regulated genes in A549 cells

| PRJNA451429 | ENA

PKA regulated genes in HEK293 cells

Project description:PKA regulated genes in HEK293 cells

| PRJNA1029958 | ENA

SMAD3 targets in A549 lung epithelial cells

Project description:TGF? activates a signal transduction cascade that results in the transcription of genes, primarily through the DNA-binding transcription factor SMAD3. The objective of this study is to identify SMAD3 binding targets and the molecular pathways affected by the TGF?1/SMAD3 signal transduction on a genome-wide scale. Cultured A549 cells at 30-50% confluence were treated with 10 uM SIS3 in dimethyl sulfoxide (DMSO), or DMSO (vehicle-only) 30 min prior to TGF?1 treatment. Cells were treated with 2 ng/mL recombinant TGF?1 for 0, 2, 12, and 24 h.

2011-06-24 | E-GEOD-26858 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data