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Bluetongue virus

ABSTRACT: Bluetongue virus Genome sequencing and assembly

PROVIDER: PRJNA548474 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR9691940.fastq.gz	Fastqsanger.gz
	SRR9691941.fastq.gz	Fastqsanger.gz
	SRR9691942.fastq.gz	Fastqsanger.gz
	SRR9691943.fastq.gz	Fastqsanger.gz
	SRR9691944.fastq.gz	Fastqsanger.gz

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Bluetongue virus

Project description:Bluetongue virus Genome sequencing

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Phosphoproteomic analysis of Bluetongue virus infection

Project description:Bluetongue virus causes infections in wild and domesticated ruminants, with the potential for causing significant morbidity, mortality and economic harm in both the developing and developed world. While vaccines have been developed, no treatment for acute infections exists. In this regard, a possible approach is to determine host-cell factors utilised by Bluetongue virus. We thus proceeded to characterize the phosphoproteome of BTV infected HeLa cells to elucidate the intracellular signalling pathways and identify critical host factors activated during Bluetongue virus infection.

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Project description:To comprehensively understand the characterization of bluetongue virus (BTV)-host interactome, and BTV infection and pathogenic mechanisms, RNA-seq was performed with BTV serotype 1 Y863 strain-infected and mock-infected sheep embryonic testicular cells (OA3.Ts) at 24 hours post-infection.

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Whole-transcriptome analyses of sheep embryonic testicular cells infected with bluetongue virus [RNA-Seq]

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Dendritic cell subtypes from lymph nodes and blood show contrasted gene expression programs upon Bluetongue Virus infection

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Gene expression profiles in skin biopsies of Red Deer Cervus elaphus experimentally infected with Bluetongue virus

Project description:The aim of this study is to determine differential gene expression on skin biopsies of experimentally BTV-infected hinds (Cervus elaphus) using serotypes 1 and 8 to understand the possible role that these genes play during BTV infection. Understanding the strategies used by this virus for their cellular uptake, and detection of differentially expressed transcripts in experimentally infected hosts, can provide identification of detailed information that might be used to prevent infection. Four seven-month-old red deer Cervus elaphus were kept in a P3 facility to be experimentally infected with Bluetongue virus, and 4 more red deer were kept as controls. Skin biopsies were taken at 14 days post-infection to determine gene expression in response to this virus.

2011-12-31 | E-GEOD-29737 | biostudies-arrayexpress

Bluetongue Virus MNG2/2016 segment 1-10 complete genome

Project description:Bluetongue Virus MNG2/2016 segment 1-10 complete genome

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Bluetongue Virus MNG3/2016 segment 1-10 complete genome

Project description:Bluetongue Virus MNG3/2016 segment 1-10 complete genome

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Dendritic cell subtypes from lymph nodes and blood show contrasted gene expression programs upon Bluetongue Virus infection

Project description:The gene expression in conventional and plasmacytoid dendritic cells (cDC and pDC respectively) during Bluetongue virus (BTV) infection in sheep depends on the lymphoid compartment and suggest that these cell types have a role in the physiopathology We analyzed the gene expression in lymph node pDC and cDC from 3 control and 3 BTV infected sheep at day 6 post infection, in blood pDC from 2 control and 2 BTV infected sheep at day 6 post infection, and in spleen cDC from 3 control and 2 BTV infected sheep at day 6 post infection.

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