Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Gene expression identifies metabolic and functional differences between intramuscular and subcutaneous adipocytes in cattle

ABSTRACT: Gene expression identifies metabolic and functional differences between intramuscular and subcutaneous adipocytes in cattle

PROVIDER: PRJNA564148 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Gene expression identifies metabolic and functional differences between intramuscular and subcutaneous adipocytes in cattle

Project description:To further our understanding of bovine fat depot biology we screened 5 discrete fat depots (IMF, intermuscular, omental, kidney and subcutaneous) for patterns of genome-wide gene expression

2019-12-31 | GSE136981 | GEO

Comparative Transcriptomic Profiles of Adipocyte in Differentiation Process Provide Insights into Different Mechanisms of Adipogenesis between Subcutaneous and Intramuscular Fat Tissues in Pig [mRNA-seq]

Project description:Purpose: In this study, RNA-Seq was performed on intramuscular adipocytes and subcutaneous adipocytes at 0, 2, 4, and 8 days of differentiation to find genes and miRNAs that regulate the differentiation of two types of adipocytes. Methods: High-throughput sequencing was performed with NovaSeq 6000, and 150 paired-end reads were generated.Clean reads were filtered using HISAT2. The StringTie was used to assemble the transcript and calculate fragments per kilobase million mapped reads (FPKM) value. Results: We found 30 genes that mainly regulate the differentiation of subcutaneous adipocytes and 22 genes that mainly regulate the differentiation of subcutaneous intramuscular adipocytes. A total of 17 important candidate differential miRNAs were found, of which 4 miRNAs are believed to play a regulatory role in both types of cells, and 10 and 3 act on lipid deposition in subcutaneous and intramuscular adipocytes, respectively.

2022-06-07 | GSE193607 | GEO

Bovine intramuscular adipocytes RNA-seq

Project description:Bovine intramuscular adipocytes RNA-seq

| PRJNA770998 | ENA

Developmental origins define epigenomic differences between subcutaneous and visceral adipocytes

Project description:Developmental origins define epigenomic differences between subcutaneous and visceral adipocytes

| PRJNA434651 | ENA

Bovine intramuscular adipocytes RNA-seq

Project description:RNA sequencing was performed to obtain a landscape of mRNA, circRNA, lncRNA, and miRNA of bovine intramuscular adipocytes in 4 differentiation periods.

2022-08-31 | GSE185850 | GEO

Expression data of human coronary artery perivascular adipocytes and subcutaneous adipocytes

Project description:Inflammatory crosstalk between perivascular adipose tissue and and blood vessel wall may contribute to atherosclerosis pathogenesis, and exhibits more pro-inflammatory than adipogenic phenotype than subcutaneous adipocytes. To identify a genomic basis for biologic differences, we performed genome-wide expression to identiy expression genes differentially regulated between perivascular and subcutaneous adipocytes.for biologic differences. We performed global gene expression analyses on in vitro differentiated adipocytes from human left coronary artery perivascular adipose tissue and subcutaneous adipose tissues derived from unrelated donors who were non-obese and did not have any known metabolic or atherosclerotic disease.

2013-03-15 | E-GEOD-45169 | biostudies-arrayexpress

Project description:Purpose: In this study, RNA-Seq was performed on intramuscular adipocytes and subcutaneous adipocytes at 0, 2, 4, and 8 days of differentiation to find genes and miRNAs that regulate the differentiation of two types of adipocytes. Method:The clean reads were mapped to the pig reference genome (scrofa. Sscrofa11.1) with perfect matches using Bowtie software. Annotated tRNA, rRNA, snoRNA, and snRNA sequences were filtered out, and conserved miRNAs were identified by the BLAST method against miRBase. The miRDeep2 software was used to predict new miRNAs based on the characteristics of the miRNA precursor hairpin structure. Differential expression analysis of two groups was performed using the DESeq2 R package. Differentially expressed miRNAs (DE-miRNAs) were screened with criterion of fold change > 1.5 and FDR < 0.05 using DESeq2. Target genes of DE-miRNAs were predicted by miRanda and targetscan. Results: We found 30 genes that mainly regulate the differentiation of subcutaneous adipocytes and 22 genes that mainly regulate the differentiation of subcutaneous intramuscular adipocytes. A total of 17 important candidate differential miRNAs were found, of which 4 miRNAs are believed to play a regulatory role in both types of cells, and 10 and 3 act on lipid deposition in subcutaneous and intramuscular adipocytes, respectively.

2022-06-07 | GSE193608 | GEO

Expression data of human coronary artery perivascular adipocytes and subcutaneous adipocytes

2013-03-15 | GSE45169 | GEO

Developmental origins define epigenomic differences between subcutaneous and visceral adipocytes [RNA_seq_Whole]

Project description:Developmental origins define epigenomic differences between subcutaneous and visceral adipocytes [RNA_seq_Whole]

| PRJNA434804 | ENA

Developmental origins define epigenomic differences between subcutaneous and visceral adipocytes [microarrays]

Project description:Developmental origins define epigenomic differences between subcutaneous and visceral adipocytes [microarrays]

| PRJNA434428 | ENA