Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: mRNA-sequencing of rat ovaries

PROVIDER: PRJNA577274 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR10281769_1.fastq.gz	Fastqsanger.gz
	SRR10281769_2.fastq.gz	Fastqsanger.gz
	SRR10281770_1.fastq.gz	Fastqsanger.gz
	SRR10281770_2.fastq.gz	Fastqsanger.gz
	SRR10281771_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 18

Similar Datasets

Project description:mRNA-sequencing in rat ovaries of PCOS and different treatment groups

| PRJNA1016879 | ENA

Mogrosisde V improves follicular development and ovulation in PCOS rats induced by letrozole and high-fat diet through promoting glycolysis

Project description:Polycystic ovary syndrome (PCOS) is a heterogeneous endocrine disorder characterized by hyperandrogenism, ovulatory dysfunction, and polycystic ovaries. In this study, we induced a PCOS rat model by oral administration of letrozole combined with a high-fat diet and then treated with mogroside V (MV) to evaluate the protective roles on endocrine and follicle development in PCOS rats and the underlying mechanisms. Purpose: To detect the difference of ovary transcriptome profiling between PCOS model and Control rat and to evaluate the effect of mogroside V on the transcriptome profiling of ovaries of PCOS model rats. Methods: Ovarian mRNA profiles of 15-week-old Control, PCOS and PCOS-MV group rats (4 rats per group) were generated by deep sequencing,using Illumina PE150.

2022-04-20 | GSE194398 | GEO

RNA sequencing of nos-gal4>phf7ey Drosophila ovaries

Project description:Next generation sequencing of mRNA for nos-gal4>phf7ey Drosophila ovaries

2020-08-28 | GSE150213 | GEO

Integrated analysis of mRNA-seq and miRNA-seq reveals the potential roles of sex-biased miRNA-mRNA pairs in gonad tissue of dark sleeper (Odontobutis potamophila)

Project description:We used next-generation sequencing technology to characterize mRNA-seq and miRNA-seq of testes and ovaries of Odontobutis potamophila to elucidate the molecular mechanisms of sex determination and differentiation. We were able to find miRNA-mRNA pairs using bioinformatics analysis and miRNA prediction algorithms.

2017-08-21 | GSE93019 | GEO

Transcription profiling of rat ovaries after 48 h of drug treatments.S1)1 IU PMSG + 1 IU hCG (this is the control)S2) 10 IU PMSG + 10 IU hCGS3) 40 IU PMSG + 30 IU hCG

Project description:the aim of this work is to gain insight into Ovarianhyperstimulation Syndrome. All samples were mRNA from rat ovaries after 48 h of drug treatments.S1)1 IU PMSG + 1 IU hCG (this is the control)S2) 10 IU PMSG + 10 IU hCGS3) 40 IU PMSG + 30 IU hCG

2013-01-30 | E-RZPD-7 | biostudies-arrayexpress

Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and snf[148] ovary Transcriptomes

Project description:Comparison of wild type and tumorous ovaries reveals that tumors inappropriately express a large number of testis genes mRNA profiles of ovaries from 0-24 hour virgin wild type (WT) and 3 day old snf[148] females were generated by deep sequencing, in duplicate, using Illumina HiSeq 2500.

2015-02-17 | E-GEOD-65932 | biostudies-arrayexpress

Circular RNA expression profiles of mouse ovaries during postnatal development and the function of circular RNA epidermal growth factor receptor in granulosa cells

Project description:Here, we explored the circRNA expression profiles of adult and neonatal mouse ovaries by high-throughput sequencing. A total of 28,000 circRNAs were identified in adult and neonatal ovaries The results showed that 343 circRNAs were up-regulated and 146 circRNAs were down-regulated in adult ovaries compared with neonate ovaries.

2019-10-02 | GSE104477 | GEO

Piwi regulates the usage of alternative transcription start sites in the Drosophila ovary

Project description:Alternative transcription initiation, which refers to the transcription of a gene from different transcription start sites (TSSs), is prevalent in mammalian systems and has important biological functions. Although transcriptional regulation has been extensively studied, the mechanism that selects one TSS over others in a gene remains elusive. We discovered Piwi, an RNA-binding protein, regulated TSS usage of genes and identified 87 genes with significantly altered TSS usage (ATU) in piwi-deficient Drosophila ovaries using the cap-analysis gene expression sequencing (CAGE-seq) method. This regulation occurs in both germline and somatic cells in ovaries as well as in cultured ovarian somatic cells (OSCs). Correspondingly, RNA Pol II initiation and elongation at TSSs of ATU genes were affected in germline-piwi-knockdown ovaries and piwi-knockdown OSCs. We identified a FACT complex component, Ssrp, which is essential for mRNA elongation, as a novel interactor of Piwi in the nucleus. Temporally controlled knockdown of ssrp affected TSS usage of ATU genes whereas overexpression of ssrp partially rescued the TSS usage of ATU genes in piwi mutant ovaries. Thus, Piwi may interact with Ssrp to regulate TSS usage in Drosophila ovaries by affecting Pol II initiation and elongation.

2024-11-29 | GSE255438 | GEO

The expression profile of circRNA, lncRNA and mRNA in the testis of STZ-induced diabetic rats

Project description:The number of patients with diabetes is increasing worldwide. Diabetic testicular damage can cause spermiogenesis disorders and sexual dysfunction. We thus explored the role of circRNA, lncRNA and mRNA in diabetic testicular damage, and revealed that they could serve as effective prevention and treatment therapeutic targets. Streptozotocin (STZ) was used to generate a rat model of type 2 diabetes. Rat testicular tissues were used for circRNA, lncRNA and mRNA sequencing.

2021-03-17 | GSE169130 | GEO

Identification of the molecular basis of anti-cancer effect of Huaier.

Project description:Intervention type:DRUG. Intervention1:Huaier, Dose form:GRANULES, Route of administration:ORAL, intended dose regimen:20 to 60/day by either bulk or split for 3 months to extended term if necessary. Control intervention1:None. Primary outcome(s): For mRNA libraries, focus on mRNA studies. Data analysis includes sequencing data processing and basic sequencing data quality control, prediction of new transcripts, differential expression analysis of genes. Gene Ontology (GO) and the KEGG pathway database are used for annotation and enrichment analysis of up-regulated genes and down-regulated genes. For small RNA libraries, data analysis includes sequencing data process and sequencing data process QC, small RNA distribution across the genome, rRNA, tRNA, alignment with snRNA and snoRNA, construction of known miRNA expression pattern, prediction New miRNA and Study of their secondary structure Based on the expression pattern of miRNA, we perform not only GO / KEGG annotation and enrichment, but also different expression analysis.. Timepoint:RNA sequencing of 240 blood samples of 80 cases and its analysis, scheduled from June 30, 2022..

| 2612481 | ecrin-mdr-crc

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data