Molecular profiling of stem cell-like female germ line cells in Drosophila delineates networks important for stemness and differentiation
Ontology highlight
ABSTRACT:
PROVIDER: PRJNA577938 | ENA |
REPOSITORIES: ENA
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| SRR10294527_1.fastq.gz | Fastqsanger.gz | |||
| SRR10294527_2.fastq.gz | Fastqsanger.gz | |||
| SRR10294528_1.fastq.gz | Fastqsanger.gz | |||
| SRR10294528_2.fastq.gz | Fastqsanger.gz | |||
| SRR10294529_1.fastq.gz | Fastqsanger.gz |
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Project description:We characterize the transcriptome of germline stem cell (GSC)-like cells isolated from bag of marbles (bam) mutant Drosophila ovaries by next generation RNA sequencing (RNA-seq) and compare it to the transcriptome of germline cells isolated from wild type ovaries. We further refine this dataset by utilizing an RNA-immunoprecipitation strategy to identify transcripts bound to the master differentiation factor Bam.
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