Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

AIB1D4 role in early breast cancer progression

ABSTRACT: AIB1D4 role in early breast cancer progression

PROVIDER: PRJNA578942 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR10331000_1.fastq.gz	Fastqsanger.gz
	SRR10331000_2.fastq.gz	Fastqsanger.gz
	SRR10331001_1.fastq.gz	Fastqsanger.gz
	SRR10331001_2.fastq.gz	Fastqsanger.gz
	SRR10331002_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 54

Similar Datasets

The role AIB1D4 cistrome in early breast cancer progression

Project description:The role AIB1D4 cistrome in early breast cancer progression

| PRJNA579385 | ENA

The role of AIB1D4 cistrome in early breast cancer progression

Project description:The role of AIB1D4 cistrome in early breast cancer progression

| PRJNA604234 | ENA

AIB1D4 role in early breast cancer progression

Project description:We report the role of AIB1D4 in early stage breast cancer progression. Using CRISPR editing, we generated isogeneic cell lines that only express AIB1D4 and not full length AIB1 then extracted RNA for sequencing from cell lines and mamary fat pad xenografts in SCID/Beige mice. Data was aligned to Hg19 with STAR and processed with EdgeR.

2020-11-08 | GSE139270 | GEO

HOTAIR Modulated Pathways in Early-Stage Breast Cancer Progression

Project description:HOTAIR Modulated Pathways in Early-Stage Breast Cancer Progression

| PRJNA758976 | ENA

The role of UBE2T in breast cancer growth and progression

Project description:The role of UBE2T in breast cancer growth and progression

| PRJNA658487 | ENA

RBMS1 regulates breast cancer progression

Project description:RBMS1 regulates breast cancer progression

| PRJNA759645 | ENA

RBM7 regulates breast cancer progression

Project description:RBM7 regulates breast cancer progression

| PRJNA1046479 | ENA

HOTAIR Modulated Pathways in Early-Stage Breast Cancer Progression

Project description:The long-non-coding HOX transcript antisense intergenic RNA (HOTAIR) was identified as significantly upregulated in breast ductal carcinoma in situ (DCIS). The aim of this study was to characterize the phenotypic effects and signaling pathways modulated by HOTAIR in early-stage breast cancer progression. We determined that HOTAIR induces premalignant phenotypic changes by increasing cell proliferation, migration, invasion and in vivo growth in normal and DCIS breast cell lines. Transcriptomic studies (RNA-seq) identified the main signaling pathways modulated by HOTAIR which include bioprocesses related to cell migration, epithelial to mesenchymal transition, extracellular matrix remodeling and activation of HIF1A, AP1 and FGFR signaling pathways among others. Similar pathways were identified as activated in primary invasive breast carcinomas with HOTAIR over-expression. We conclude that HOTAIR over-expression behaves as a positive regulator of cell growth and migration both in normal and DCIS breast cells involved with early-stage breast cancer progression.

2021-11-01 | GSE183058 | GEO

Breast Cancer Family Registry Early-onset Breast Cancer GWAS

Project description:Breast Cancer Family Registry Early-onset Breast Cancer GWAS

| PRJNA454751 | ENA

Breast Cancer Family Registry Early-onset Breast Cancer GWAS

Project description:Breast Cancer Family Registry Early-onset Breast Cancer GWAS

| PRJNA454752 | ENA