Project description:Either WT or muMT KO mice were infected with UPEC trans urethrealy twice 1 hour apart and culled 6 hours later. Kidneys were subsequently perfused, RNA extracted and analysed via RNASeq
Project description:Transcriptional profiling to map the changes in placental function subsequent to maternal experimental UTI that result in intrauterine growth restriction. One condition experiment: 2 biological replicates of placenta from mice with maternal experimental UTI, 2 biological replicates of placenta from mice with sham UTI.
Project description:Lysosome-enriched fractions from the liver of Cln8 KO mice and WT mice. Included are four datasets: 1. Lysosome-enriched fraction from the liver of Cln8 KO mice, replicate 1 (CLN8_KO_1). 2. Lysosome-enriched fraction from the liver of Cln8 KO mice, replicate 2 (CLN8_KO_2). 3. Lysosome-enriched fraction from the liver of WT mice, replicate 1 (WT_1). 4. Lysosome-enriched fraction from the liver of WT mice, replicate 2 (WT_2).
Project description:TMT analysis of proteomic changes in the gastrocnemius skeletal muscles of WT and Bmal1-KO mice, and Bmal1-KO mice rescued with AAV-mediated muscle-specific expression of Bmal1.
Project description:To explore global gene expression using microarray analysis in mTEC's isolated from MBD1 WT and MBD1 KO mice mTECs were sorted by flow cytometry from 30 day old MBD1 WT and KO Mice. 4 biological replicates were performed for both MBD1 WT and KO mice (1 replicate of each failed quality control and wasd removed from the analysis).