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Gene expression analysis in fly ovaries from wuho mutant

ABSTRACT: Gene expression analysis in fly ovaries from wuho mutant

PROVIDER: PRJNA598567 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR10814924.fastq.gz	Fastqsanger.gz
	SRR10814925.fastq.gz	Fastqsanger.gz
	SRR10814926.fastq.gz	Fastqsanger.gz
	SRR10814927.fastq.gz	Fastqsanger.gz

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Project description:Foxl2 is a forkhead transcription factor expressed only in the female, but not in the male gonad. We have created mice homozygous mutant for the Foxl2 gene (KO) as well as mice carrying a conditional mutant Foxl2 allele (floxed). The expression profiles of conventional Foxl2 knockout and wildtype ovaries were compared at P3, using the Affy Mouse Genome 430 2.0 Array. Adult wildtype and conditional mutant (Foxl2 floxed x RosaCre-EBD treated with tamoxifen) ovaries were compared to adult wildtype testes using the Affymetrix Mouse Gene 1.0 ST Array. Both experiments (KO/WT P3 and Mutant/WT/Testis Adult were also compared to each other.)

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