Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Nasal Microbiome

PROVIDER: PRJNA600228 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR10857600_1.fastq.gz	Fastqsanger.gz
	SRR10857600_2.fastq.gz	Fastqsanger.gz
	SRR10857601_1.fastq.gz	Fastqsanger.gz
	SRR10857601_2.fastq.gz	Fastqsanger.gz
	SRR10857602_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 60

Similar Datasets

Single cell RNA sequencing in Staphylococcus epidermidis-inoculated nasal epithelial cells

Project description:We report the application of single cell RNA sequencing technology for high-throughput profiling of nasal microbiome Staphylococcus epidermidis in human nasal epithelial cells.

2021-02-26 | GSE167509 | GEO

Host-Microbe Interactions in the Nasal Cavity of Dogs with Chronic Idiopathic Rhinitis

Project description:Chronic rhinitis (CR) is a frustrating clinical syndrome in dogs and our understanding of the disease pathogenesis in is limited. Increasingly, host-microbe interactions are considered key drivers of clinical disease in sites of persistent mucosal inflammation such as the nasal and oral cavities. Therefore, we applied next generation sequencing tools to interrogate abnormalities present in the nose of dogs with CR and compared immune and microbiome profiles to those of healthy dogs. Host nasal cell transcriptomes were evaluated by RNA sequencing, while microbial communities were assessed by 16S rRNA sequencing. Correlation analysis was then used to identify significant interactions between nasal cell transcriptomes and the nasal microbiome and how these interactions were altered in animals with CR. Notably, we observed significant downregulation of multiple genes associated with ciliary function in dogs with CR, suggesting a previously undetected role for ciliary dysfunction in this syndrome. We also found significant upregulation of immune genes related to the TNF-a and interferon pathways. The nasal microbiome was also significantly altered in CR dogs, with overrepresentation of several potential pathobionts. Interactome analysis revealed significant correlations between bacteria in the genus Porphyromonas and the upregulated host inflammatory responses in dogs with CR, as well as defective ciliary function which was correlated with Streptococcus abundance. These findings provide new insights into host-microbe interactions in a canine model of CR and indicate the presence of potentially causal relationships between nasal pathobionts and the development of nasal inflammation and ciliary dysfunction.

2024-08-08 | GSE255529 | GEO

Test SynCom strains interaction 211223

Project description:Microbial Synthetic Community resembling the Nasal human microbiome

2024-01-18 | MSV000093885 | MassIVE

GNPS - Test SynCom strains interaction 211223

Project description:Microbial Synthetic Community resembling the Nasal human microbiome

2024-01-18 | MSV000093885 | GNPS

In-depth proteomic analysis of nasal fluids from patients with chronic rhinosinusitis and nasal polyps by data-independent acqusition

Project description:Antibiotics are commonly prescribed to treat chronic rhinosinusitis (CRS). However, the effects of antibiotics on the microbiome and secreted proteome remain unknown in regard to CRS.We analyzed the effects of antibiotics on the nasal secreted proteome inthe context of CRS using data-independent acqusition proteomics approach.

2021-09-09 | PXD018960 | Pride

Project description:Bovine nasal microbiome

| PRJNA1049020 | ENA

nasal microbiome

Project description:nasal microbiome Metagenome

| PRJNA488874 | ENA

Project description:Bovine nasal microbiome

| PRJNA1047266 | ENA

Project description:Human Nasal Microbiome

| PRJNA704182 | ENA

Project description:Nasal Microbiome and Nasal Host-Microbiota Interactions

| PRJNA746950 | ENA