Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Fattening experiment of Tan Sheep in Ningxia

PROVIDER: PRJNA600999 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR10897943_1.fastq.gz	Fastqsanger.gz
	SRR10897943_2.fastq.gz	Fastqsanger.gz
	SRR10897944_1.fastq.gz	Fastqsanger.gz
	SRR10897944_2.fastq.gz	Fastqsanger.gz
	SRR10897945_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 72

Similar Datasets

Transcriptome analysis reveals the molecular regulatory network of dietary supplementation with succinate on muscle fiber characteristics and meat quality in Tan sheep

Project description:To investigate the impact of adding succinate to the diet on the production performance, meat quality, muscle fiber characteristics, and transcriptome of the longissimus dorsi muscle in Tan sheep, 36 Tan sheep were selected and fed with different levels of succinate (0%, 0.5%, 1.0%, 2.0%) for a 60-day trial period. Overall, compared to the control group, the addition of succinate to the diet improved the production performance, slaughter performance, and meat quality of Tan sheep. It significantly increased dry matter intake, carcass weight, eye muscle area, and the GR value while significantly reducing the shear force and cooking loss of the longissimus dorsi muscle (p<0.05). Furthermore, the addition of succinate to the diet altered the muscle fiber characteristics of the longissimus dorsi muscle in Tan sheep, significantly increasing the fiber diameter and cross-sectional area of type I and type IIa muscle fibers (p<0.05). The addition of 1.0% succinate to the diet altered the transcriptome of the longissimus dorsi muscle in Tan sheep, with 741 differentially expressed genes identified compared to the control group. These differentially expressed genes were involved in various pathways related to lipid metabolism, energy metabolism, and muscle development, such as insulin secretion, insulin resistance, cAMP signaling pathway, PI3K-Akt signaling pathway, and FoxO signaling, among others. In summary, succinate plays a crucial role in regulating energy metabolism, protein deposition, and glucose and lipid metabolism homeostasis in Tan sheep through insulin signaling pathways and the interaction of muscle cell factors. By modulating the expression of relevant genes, succinate improves the muscle fiber characteristics of Tan sheep, thereby enhancing production performance and meat quality.

2023-11-26 | GSE248353 | GEO

Project description:Tan-sheep liver transcriptomics

| PRJNA1158691 | ENA

Tan sheep and Hu sheep rumen microbe

Project description:Tan sheep and Hu sheep rumen microbe Metagenome

| PRJNA1029673 | ENA

Rumen microbe

Project description:Tan sheep and Hu sheep rumen microbe MAGs

| PRJNA1029728 | ENA

Project description:Rumen microbial diversity of Tan sheep

| PRJNA974932 | ENA

Project description:Rumen microbial diversity of Tan sheep