Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Single Cell and Spatial Analysis of Human Squamous Cell Carcinoma [ST]

ABSTRACT: Single Cell and Spatial Analysis of Human Squamous Cell Carcinoma [ST]

PROVIDER: PRJNA603104 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR11832808_1.fastq.gz	Fastqsanger.gz
	SRR11832808_2.fastq.gz	Fastqsanger.gz
	SRR11832809_1.fastq.gz	Fastqsanger.gz
	SRR11832809_2.fastq.gz	Fastqsanger.gz
	SRR11832810_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 56

Similar Datasets

Single Cell and Spatial Analysis of Human Squamous Cell Carcinoma [ST]

Project description:To define the cellular composition and spatial architecture of the tumor micoenvironment, we combined single-cell RNA-sequencing, spatial transcriptomics, and multiplexed ion-beam imaging from 10 patient cutaneous squamous cell carcinoma tumors and site-matched normal skin

2020-06-22 | GSE144239 | GEO

Single Cell and Spatial Analysis of Human Squamous Cell Carcinoma [WES]

2020-06-22 | GSE144237 | GEO

Single Cell and Spatial Analysis of Human Squamous Cell Carcinoma

Project description:Single Cell and Spatial Analysis of Human Squamous Cell Carcinoma

| PRJNA603101 | ENA

Single Cell and Spatial Analysis of Human Squamous Cell Carcinoma [CRISPR screen]

2020-06-22 | GSE144238 | GEO

Single Cell and Spatial Analysis of Human Squamous Cell Carcinoma [single-cell RNA-seq]

2020-06-22 | GSE144236 | GEO

Single Cell and Spatial Analysis of Human Squamous Cell Carcinoma [WES]

Project description:Single Cell and Spatial Analysis of Human Squamous Cell Carcinoma [WES]

| PRJNA603106 | ENA

Spatial intratumor heterogeneity of epigenetic alterations in esophageal squamous cell carcinoma

Project description:Esophageal squamous cell carcinoma (ESCC) is among the most common malignancies, but little is known about the spatial intratumor heterogeneity (ITH) and the temporal clonal evolutionary processes in this cancer. Interestingly, the epigenetic profiling also showed strong evidence of spatial ITH, and the phyloepigenetic trees were extremely similar with the phylogenetic ones, indicating the interplay and co-dependency of genetic and epigenetic alterations in ESCC. We found that several genes were both mutated and hypermethylated at their promoters, such as ASXL1 and EPHA7. Our integrated investigations of the spatial ITH and the temporal clonal evolution might provide insights into developing biomarkers for early diagnosis of ESCC, as well as personalized therapeutic targets for treating this malignancy. DNA methylation profiles of 12 tumor regions and 2 matched normal esophageal epithelial tissues from three M-WES-examined ESCC cases (ESCC01, ESCC03 and ESCC05) were performed using Illumina Infinium HumanMethylation450K platform (Illumina, San Diego, CA) at the Epigenome Center of University of Southern California.

2016-08-20 | E-GEOD-79366 | biostudies-arrayexpress

Single Cell and Spatial Analysis of Human Squamous Cell Carcinoma [CRISPR screen]

Project description:Single Cell and Spatial Analysis of Human Squamous Cell Carcinoma [CRISPR screen]

| PRJNA603105 | ENA

Single Cell and Spatial Analysis of Human Squamous Cell Carcinoma [single-cell RNA-seq]

Project description:Single Cell and Spatial Analysis of Human Squamous Cell Carcinoma [single-cell RNA-seq]

| PRJNA603103 | ENA