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RNA-seq and H3K9me2 ChIP-seq of postnatal male germ cells

ABSTRACT: RNA-seq and H3K9me2 ChIP-seq of postnatal male germ cells

PROVIDER: PRJNA622963 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR11477000.fastq.gz	Fastqsanger.gz
	SRR11477001.fastq.gz	Fastqsanger.gz
	SRR11477002.fastq.gz	Fastqsanger.gz
	SRR11477003.fastq.gz	Fastqsanger.gz
	SRR11477004.fastq.gz	Fastqsanger.gz

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Genome wide map of H3K9me2 in postnatal male germ cells

Project description:We report the H3K9me2 distribution profile with ChIP sequencing of postnatal male germ cells. Histone modification levels are dynamically controlled during mammalian spermatogenesis. We found that H3K9 demethylases, Jmjd1a and Jmjd1b catalyze H3K9 demethylation in prospermatogonia. Combined loss of Jmjd1 enzymes disturbed prospermatogonia to spermatogonia transition in mice. To examine a role of Jmjd1 in prospermatogonia to spermatogonia transition, we performed RNA-seq and ChIP-seq analyses using postnatal germ cells at P3 and P7.

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RNA-seq and H3K9me2 ChIP-seq of postnatal male germ cells

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