Kentucky assay: cigarette smoke
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ABSTRACT:
PROVIDER: PRJNA626542 | ENA |
REPOSITORIES: ENA
Similar Datasets
Project description:Kentucky assay: artificial cigarette smoke odor
| PRJNA626543 | ENA
Project description:Mice have 1,100 odorant receptors. Nearly all are orphan receptors. The pattern of receptor responses to odors is the input that allows the brain to detect and discriminate odors The Kentucky assay measures the function of each of the 1,100 odorant receptors and 14 TAARs in vivo.
2020-04-20 | GSE148916 | GEO
Project description:Mice have 1,100 odorant receptors. Nearly all are orphan receptors. The pattern of receptor responses to odors is the input that allows the brain to detect and discriminate odors The Kentucky assay measures the function of each of the 1,100 odorant receptors and 14 TAARs in vivo.
2020-04-20 | GSE148915 | GEO
Project description:Gene expression patterns were assessed in normal human bronchial epithelial (NHBE) cells exposed to cigarette smoke from a reference cigarette (2R4F, University of Kentucky) and a typical American brand of "light" cigarettes ("Lights") in order to develop a better understanding of the genomic impact of tobacco exposure, which can ultimately define biomarkers that discriminate tobacco-related effects and outcomes in a clinical setting. NHBE cells were treated with whole cigarette smoke for 15 minutes and alterations to the transcriptome assessed at 2, 4, 8 and 24 hours post-exposure using high-density oligonucleotide microarrays. Keywords: time course, cigarette smoke exposure
2008-03-04 | GSE10700 | GEO
Project description:normal human bronchial epithelial cultures from two cultures in parallel exposed to cigarette smoke (CS) or air (mock) at timepoints 4 hours and 24 hours. Keywords = cigarette smoke Keywords = microarray Keywords = bronchial cell Keywords = tobacco Keywords: time-course
2005-02-23 | GSE2302 | GEO
Project description:Mammalian females are born with a finite number of non-renewing primordial follicles, the majority of which remain in a quiescent state for many years. Due to their non-renewing nature, these M-bM-^@M-^\restingM-bM-^@M-^] oocytes are particularly vulnerable to xenobiotic insult, resulting in premature ovarian senescence and the formation of dysfunctional oocytes. In this study we characterised the mechanisms behind cigarette smoke induced ovotoxicity, which is characterised by primordial follicle depletion. C57BL/6 5 week old female mice were exposed to cigarette smoke five times per week, for 12-18 weeks using a custom-designed and purpose-built nose-only, directed flow inhalation and smoke-exposure system. This was done in the hopes of gaining a better understanding of the mechanisms underpinning cigarette smoke induced ovotoxicity. C57BL/6 5 week old female mice were exposed to cigarette smoke (twelve 3R4F reference cigarettes (University of Kentucky, USA) twice/day, 2.7 mg particulate matter) five times per week, for 12-18 weeks using a custom-designed and purpose-built nose-only, directed flow inhalation and smoke-exposure system. Their ovaries were then collected for RNA extraction and hybridization on an Illumina Sentrix Mouse ref-8 v2 Beadchip
2012-12-13 | E-GEOD-42889 | biostudies-arrayexpress