Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Competing endogenous RNA expression profiling in decidua after LPS treatment

ABSTRACT: Competing endogenous RNA expression profiling in decidua after LPS treatment

PROVIDER: PRJNA631018 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Competing endogenous RNA expression profiling in decidua after LPS treatment

Project description:To investigate the competing endogenous RNA expression changes in decidua under the inflammatory reaction, LPS (100 μg/kg body weight) was intraperitoneally injected into the mice at 15 days of pregnancy. Premature births has been found after approximately 48 h of treatment. When bleeding found in vagina, the decidua were selected in asepsis condition, and total RNA was isolated to analyze the expression of competing endogenous RNA compared with cesarean sections.

2023-05-06 | GSE150066 | GEO

Long noncoding RNA related-competing endogenous RNAs in retinal pigment epithelial cells induced by clusterin

Project description:long noncoding RNAs (lncRNAs) play crucial roles in regulating gene expression by acting as competing endogenous RNAs (ceRNAs).

2016-09-22 | GSE87167 | GEO

Rpph1 regulated Cdc42 and modulated hippocampal pyramidal neurons by competing endogenous miR-330-5p

Project description:To build up competing endogenous RNA regulatory network based on APP/PS1 transgenic mice model and verify Rpph1, miR-330-5p and Cdc42 interaction

2017-06-10 | GSE87550 | GEO

Competing endogenous RNA expression dataset from placenta tissues of normal human and patients with severe preeclampsia.

Project description:We used microarray to detail Competing endogenous RNA expreession in placenta tissues from normal human and patients with severe preeclampsia

2019-06-27 | GSE102897 | GEO

Larix decidua

Project description:Larix decidua overview

| PRJNA74479 | ENA

NACER, a liver-specific lncRNA, functions as Nrf2-activating competing endogenous RNA for Plk2 and p21cip1

Project description:LncRNA for anti-oxidative capacity control has not been discovered yet. Nrf2 is a central molecule for cellular defense by increasing anti-oxidative capacity. Here, we identified a novel lncRNA named ‘NACER’ (Nrf2 Activating Competing Endogenous RNA) transcribed from an upstream region of MIR122. NACER existed in the cytoplasm, suggestive of its function as competing endogenous RNA (ceRNA, miRNA sponge). NACER served as ceRNA for Plk2 and p21cip1 through binding for miR-128/224, inducing Plk2/Nrf2/p21cip1 complexation for Nrf2 activation in cells under p53-activating conditions (i.e., DNA damage and serum deprivation). NACER expression was suppressed when apoptosis was initiated, being a rheostat for cell fate determination. NACER levels correlated with the recurrence free survival rate of patients with hepatocellular carcinoma after surgery. Collectively, NACER promotes Plk2 and p21cip1 translation by competing for specific miRNAs, activating Nrf2 under the surviving condition from oxidative stress, implying that NACER plays a fine-tuning rheostat for cell fate decision.

2024-05-01 | GSE115409 | GEO

Transcriptomic analysis and competing endogenous RNA network in the human endometrium between proliferative and mid-secretory phases

Project description:To identify differentially expressed transcripts (long-noncoding RNAs [lncRNAs], microRNAs [miRNAs], and mRNAs) and competing endogenous RNA (ceRNA) networks closely connected with endometrial receptivity, we analyzed gene expression profiles between the proliferative and mid-secretory endometria in fertile women.

2021-02-24 | GSE167325 | GEO

Larix decidua

Project description:Larix decidua Microsporocytes Transcriptome

| PRJNA624007 | ENA

Construction of competing endogenous RNA networks in systemic lupus erythematosus by integrated analysis

Project description:SLE is a disease characterised by immune inflammation and damage to multiple organs. Recent investigations have linked competing endogenous RNAs (ceRNAs) to lupus. However, the exact mechanism through which the ceRNAs network affects SLE is still unclear. This study aims to investigate the regulatory functions of the ceRNAs network, which are important pathways that control the pathophysiological processes of SLE. We constructed a novel circRNA-miRNA-mRNA ceRNA network (HSA circ 0000345- HSA miR-22-3-P-ESR1/SIRT1) that may have a major impact on SLE.

2024-05-10 | GSE266651 | GEO

Construction of competing endogenous RNA networks in systemic lupus erythematosus by integrated analysis

Project description:Construction of competing endogenous RNA networks in systemic lupus erythematosus by integrated analysis

| PRJNA1108188 | ENA