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Transcriptomic analysis of endothelial progenitor cells (EPCs) isolated from mice exposed to concentrated air pollution particles (CAPS) [miRNA-seq]

ABSTRACT: Transcriptomic analysis of endothelial progenitor cells (EPCs) isolated from mice exposed to concentrated air pollution particles (CAPS) [miRNA-seq]

PROVIDER: PRJNA641371 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR12073582.fastq.gz	Fastqsanger.gz
	SRR12073583.fastq.gz	Fastqsanger.gz
	SRR12073584.fastq.gz	Fastqsanger.gz
	SRR12073585.fastq.gz	Fastqsanger.gz
	SRR12073586.fastq.gz	Fastqsanger.gz

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Transcriptomic analysis of endothelial progenitor cells (EPCs) isolated from mice exposed to concentrated air pollution particles (CAPS) [miRNA-seq]

Project description:Mice were exposed to filtered air or CAPs for 30 days and then bone marrow-derived EPCs isolated and cultured for 12 days. RNAs isolated from these mice were used for RNA seq analysis.

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Transcriptomic analysis of endothelial progenitor cells (EPCs) isolated from mice exposed to concentrated air pollution particles (CAPS) [mRNA-seq]

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Project description:Transcriptomic analysis of endothelial progenitor cells (EPCs) isolated from mice exposed to concentrated air pollution particles (CAPS) [mRNA-seq]

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Transcriptomic analysis of endothelial progenitor cells (EPCs) isolated from mice exposed to concentrated air pollution particles

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Transcriptomic analysis of endothelial progenitor cells (EPCs) isolated from mice exposed to concentrated air pollution particles

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Expression data from human healthy and lupus EPCs/CACs, and healthy CD133+ bone marrow EPCs

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Expression data from endothelial progenitor cells (EPCs)

Project description:Endothelial progenitor cells (EPCs) are a group of cells which can differentiate to mature endothelial cells in a certain culture condition, and were first isolated from adult human peripheral blood by Asahara et al. in 1997. EPCs have a critical role in the restoration of injured vessel endothelium and the neovascularization in the area of ischemia injury. Recently, the role of androgens in the proliferation, differentiation and adhesion of EPCs is more and more focused. Dihydrotestosterone (DHT) is a kind of unmetabolizable androgen. We used microarrays to detail the global programme of gene expression underlying cellularisation and identified distinct classes of regulated genes in DHT-treated EPCs.

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