Project description:Male Sprague-Dawley rats [Crl:CD®(SD)IGS BR], weighing ~250 g at study initiation were obtained from Charles River Laboratories, Inc. (Wilmington, MA). Rats were housed singly in ventilated, stainless steel, wire-bottom hanging cages and fed non-certified Rodent Chow (Harlan Labs, Madison, WI) and water ad libitum and acclimated for at least 5 days after arrival. Rats were randomly assigned to various treatment groups (3 rats/group) and were dosed once daily by oral gavage with vehicle (0.2% hydroxypropylmethylcellulose at a dose volume of 10 ml/kg) or with 30, 100, or 200 mg/kg of A-998679. All rats were fasted overnight after their last dose, weighed and sacrificed under isoflurane anesthesia. Liver and small intestine (jejunum) were flash frozen in liquid nitrogen and stored at −80°C until processing for gene expression profiling on the Affymetrix platform.

2012-08-04 | GSE39850 | GEO

5 Day Oral Study of A-998679 in Male Sprague Dawley Rats (liver)

2012-07-24 | GSE39525 | GEO

Rattus norvegicus strain:Sprague-Dawley rats

Project description:Rattus norvegicus strain:Sprague-Dawley rats Genome sequencing

| PRJNA686507 | ENA

Rattus norvegicus strain:Sprague-Dawley rats

Project description:Rattus norvegicus strain:Sprague-Dawley rats Raw sequence reads

| PRJNA687124 | ENA

5 Day Oral Study of A-998679 in Male Sprague Dawley Rats

Project description:This SuperSeries is composed of the following subset Series: GSE39525: 5 Day Oral Study of A-998679 in Male Sprague Dawley Rats (liver) GSE39850: 5 Day Oral Study of A-998679 in Male Sprague Dawley Rats (Jejunum) Refer to individual Series

2012-08-03 | E-GEOD-39875 | biostudies-arrayexpress

Rattus norvegicus strain:Sprague-Dawley rats

Project description:Rattus norvegicus strain:Sprague-Dawley rats Transcriptome or Gene expression

| PRJNA565669 | ENA