Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Ribosomal profiling of WT and mORF4/NBDY KO hearts

ABSTRACT: Ribosomal profiling of WT and mORF4/NBDY KO hearts

PROVIDER: PRJNA647908 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR12300124_1.fastq.gz	Fastqsanger.gz
	SRR12300124_2.fastq.gz	Fastqsanger.gz
	SRR12300125.fastq.gz	Fastqsanger.gz
	SRR12300126_1.fastq.gz	Fastqsanger.gz
	SRR12300126_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 27

Similar Datasets

Ribosomal profiling of WT and mORF4/NBDY KO hearts

Project description:Left ventricles from the hearts of adult WT and mORR4/NBDY KO mice were obtained. Per heart, RNA-sequencing and ribosomal profiling was performed on the same heart

2020-07-23 | GSE154940 | GEO

Ribosomal profiling of WT and mORF4/NBDY KO hearts [WT_vs_mORF4-NBDYKO_RNAseq]

Project description:Ribosomal profiling of WT and mORF4/NBDY KO hearts [WT_vs_mORF4-NBDYKO_RNAseq]

| PRJNA648762 | ENA

Ribosomal profiling of WT and mORF4/NBDY KO hearts [WT_vs_mORF4-NBDYKO_RNAseq]

Project description:Left ventricles from the hearts of adult WT and mORR4/NBDY KO mice were obtained.

2020-07-27 | GSE155133 | GEO

Transcriptome of E9.5 WT and Smyd1-KO mouse hearts

Project description:Purpose: The goal of this study is to identify the differential cardiac transcriptome profiling between WT and Smyd1 null (Smyd1-KO) hearts at E9.5 using RNA-seq. Methods: mRNA profiles of E9.5 WT and Smyd1-KO mouse hearts were generated by deep sequencing, n=3 for each genotype, using Illumina HiSeq2500. The sequence reads were aligned to the mm10 reference genome using STAR via the bcbio-nextgen RNA-sequencing pipeline. Differential gene expression was determined by DEseq2. Results: 1756 genes were differentially expressed between WT and Smyd1-KO hearts [adjusted P value <0.05, |log2(Fold Change)| > 0.5], with 1130 upregulated and 626 downregulated in E9.5 Smyd1-KO hearts.

2024-04-18 | GSE260692 | GEO

ATAC-seq of E9.5 WT and Smyd1-KO mouse hearts

Project description:Purpose: The goal of this study is to identify the differential cardiac chromatin accessibility between WT and Smyd1 null (Smyd1-KO) hearts at E9.5 using ATAC-seq. Methods: Four hearts at E9.5 were pooled per genotype per replicate, and were then dissociated into single cells. 40,000 viable cells were taken for were lysed to isolate nuclei, which were treated with Tn5 transposase (Nextera DNA Sample Prep Kit, Illumina) to isolate DNA. Fragmented DNA was then amplified using bar-coded PCR primers and libraries were seuqenced. Results: 25851 differential peaks (2-fold change) were identified between E9.5 WT and Smyd1-KO hearts.

2024-04-18 | GSE260690 | GEO

RNA-seq of CCBE1 KO and WT murine hearts

Project description:CCBE1 is a secreted extracellular matrix protein expressed by epicardial cells but its role during epicardial development was still unknown.Using a Ccbe1 knockout (KO) mouse model, we observed that loss of CCBE1 leads to congenital heart defects including thinner and hyper-trabeculated ventricular myocardium. In addition, Ccbe1 mutant hearts displayed reduced proliferation of cardiomyocyte and epicardial cells. RNA-seq data of CCBE1 KO and WT murine hearts indicated deregulation of genes associated with development and morphogenesis including the epithelial-to-mesenchymal transition.

2022-10-23 | E-MTAB-12217 | biostudies-arrayexpress

RNA-seq of CCBE1 KO and WT murine hearts

Project description:RNA-seq of CCBE1 KO and WT murine hearts

| PRJEB56354 | ENA

Transcriptome of E9.5 WT and Smyd1-KO mouse hearts

Project description:Transcriptome of E9.5 WT and Smyd1-KO mouse hearts

| PRJNA1082680 | ENA

ATAC-seq of E9.5 WT and Smyd1-KO mouse hearts

Project description:ATAC-seq of E9.5 WT and Smyd1-KO mouse hearts

| PRJNA1082682 | ENA