Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Near-infrared-emitting nanoparticles activate collagen synthesis via TGFβ signaling

ABSTRACT: Near-infrared-emitting nanoparticles activate collagen synthesis via TGFβ signaling

PROVIDER: PRJNA648300 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR12316124_1.fastq.gz	Fastqsanger.gz
	SRR12316124_2.fastq.gz	Fastqsanger.gz
	SRR12316125_1.fastq.gz	Fastqsanger.gz
	SRR12316125_2.fastq.gz	Fastqsanger.gz
	SRR12316126_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 30

Similar Datasets

Near-infrared-emitting nanoparticles activate collagen synthesis via TGFβ signaling

Project description:We describe the novel synthesis Ag2S nanoparticles (NPs) by using a sonochemical method and reveal the effects of NIR irradiation on the enhancement of the production of collagen through NIR-emitting Ag2S NPs. We also synthesized Li-doped Ag2S NPs that exhibited significantly increased emission intensity because of their enhanced absorption ability in the UV - NIR region.

2020-07-25 | GSE155027 | GEO

Gene expression in a 3-dimensional reconstructed human corneal epithelial tissue after near-infrared irradiation simulating solar near-infrared radiation that reaches human tissues on the Earth’s surface

2016-01-05 | GSE76500 | GEO

Project description:To clarify the effects of near-infrared radiation, we assessed DNA microarray after water-filtered broad-spectrum near-infrared (1100-1800 nm together with a water-filter that excludes wavelengths 1400-1500 nm) irradiation. We performed 5 rounds of near-infrared irradiation (at 10 J âcm2) using 2 sets of transparent polycarbonate plates, one to block UV and the other to block both UV and near-infrared.

2016-01-05 | E-GEOD-76500 | biostudies-arrayexpress

Collagen type VI regulates TGFβ bioavailability in skeletal muscle

Project description:Collagen VI-related disorders (COL6-RDs) are a group of rare muscular dystrophies caused by pathogenic variants in collagen VI genes. ¬¬Collagen type VI is a heterotrimeric, microfibrillar component of the muscle extracellular matrix (ECM), predominantly secreted by resident fibroadipogenic precursor cells in skeletal muscle. Collagen VI absence or mislocalization in the skeletal muscle ECM underlies the non-cell autonomous dystrophic changes and dysfunction in skeletal muscle in COL6-RDs with an as of yet elusive direct mechanistic link between the ECM and myofiber dysfunction. Here, we derive a novel mouse model of COL6-RD, Col6a2-/- mice, and conduct a comprehensive natural history study in male and female animals aged to 60 weeks of age. Col6a2-/- mice have a normal lifespan but develop muscle weakness based on standardized behavioral tests (grip and hanging wire test), muscle atrophy with histologic hallmarks of muscular dystrophy, and reduced muscle force prodcution on physiologic parameters. We also report a robust dysregulation of TGFβ pathway early in the disease process and thus propose a new mechanism for pathogenesis of the disease that links the ECM regulation of TGFβ with downstream skeletal muscle abnormalities, paving the way for developing therapeutics that target this pathway.

2023-12-04 | GSE228223 | GEO

Collagen type VI regulates TGFβ bioavailability in skeletal muscle

Project description:Collagen type VI regulates TGFβ bioavailability in skeletal muscle

| PRJNA948852 | ENA

Gene expression in a 3-dimensional human epidermal tissue culture model after water-filtered near-infrared irradiation

Project description:To clarify the effects of near-infrared radiation, we assessed DNA microarray after water-filtered near-infrared (1100-1800 nm together with a water-filter that excludes wavelengths 1400-1500 nm) irradiation.

2016-03-19 | GSE79394 | GEO

Near-infrared fluorescent reporter stem cell model

Project description:Near-infrared fluorescent reporter stem cell model

| PRJEB51223 | ENA

Molecular Basis of Infrared Detection by Snakes

Project description:Snakes possess a unique sensory system for detecting infrared radiation, enabling them to generate a ‘thermal image’ of predators or prey. Infrared signals are initially received by the pit organ, a highly specialized facial structure that is innervated by nerve fibers of the somatosensory system. How this organ detects and transduces infrared signals into nerve impulses is not known. Here we use an unbiased transcriptional profiling approach to identify TRPA1 as the infrared receptor on sensory neurons that innervate the pit organ. TRPA1 from pit bearing snakes (rattlesnakes and pythons) are the most heat sensitive vertebrate ion channels thus far identified, consistent with their role as primary transducers of infrared stimuli in these animals. Thus, snakes detect infrared signals through a mechanism involving radiant heating of the pit organ, rather than photochemical transduction. These findings illustrate the broad evolutionary tuning of TRP channels as thermosensors in the vertebrate nervous system.

2010-03-16 | GSE19911 | GEO

Effects of far-infrared rays on normal prostate epithelial cells (PrEC)

Project description:Far-infrared rays activated DNA repair genes in human prostate epithelial cells after 7 or 12 days' exposure to far-infrared rays. As far-infrared rays emitter, synthetic/natural rubber (RB) was used.

2017-03-14 | GSE15259 | GEO

Molecular Basis of Infrared Detection by Snakes

2010-03-16 | E-GEOD-19911 | biostudies-arrayexpress