Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Identification and comparison of circular RNAs in Preeclampsia

PROVIDER: PRJNA665923 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR12744710_1.fastq.gz	Fastqsanger.gz
	SRR12744710_2.fastq.gz	Fastqsanger.gz
	SRR12744711_1.fastq.gz	Fastqsanger.gz
	SRR12744711_2.fastq.gz	Fastqsanger.gz
	SRR12744712_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 12

Similar Datasets

Genome-wide identification of myoblast circular RNAs

Project description:Genome-wide identification of myoblast circular RNAs

| PRJNA427494 | ENA

Project description:Identification and characterization of MCF01A circular RNAs

| PRJNA290555 | ENA

Identification and evolutionary comparison of circular RNAs in five mammalian species and three organs.

Project description:Identification and evolutionary comparison of circular RNAs in five mammalian species and three organs.

| PRJNA680762 | ENA

Project description:Global identification of circular RNAs during zebrafish embryogenesis

| PRJNA556992 | ENA

Homo sapiens

Project description:Expanded identification and characterization of mammalian circular RNAs

| PRJNA223608 | ENA

Identification of circular RNAs in amyotrophic lateral sclerosis

Project description:Identification of circular RNAs in amyotrophic lateral sclerosis

| PRJNA890244 | ENA

Homo sapiens

Project description:Identification of Senescence-Associated Circular RNAs (SAC-RNAs) reveals senescence suppressor CircPVT1

| PRJNA339301 | ENA

The oncogenic role of circPVT1 in head and neck squamous cell carcinoma is mediated through the mutant p53/YAP/TEAD complex

Project description:Background: circular RNAs are a class of endogenous RNAs with various functions in eukaryotic cells. Worthy of note, circular RNAs play a critical role in cancer. Currently, nothing is known about the role of circular RNAs in head and neck squamous cell carcinoma (HNSCC). The identification of circular RNAs in HNSCC might become useful for diagnostic and therapeutic strategies in HNSCC. Results: Using samples from 115 HNSCC patients, we find that circPVT1 is over-expressed in tumors compared to matched non-tumoral tissues, with particular enrichment in patients with TP53 mutations. The circPVT1 up- and down-regulation determine, respectively, an increase and a reduction of the malignant phenotype in HNSCC cell lines. We show that circPVT1 expression is transcriptionally enhanced by the mut-p53/YAP/TEAD complex. CircPVT1 acts as an oncogene modulating the expression of miR-497-5p and genes involved in the control of cell proliferation. Conclusions: This study shows the oncogenic role of circPVT1 in HNSCC, extending the current knowledge about the role of circular RNAs in cancer.

2017-12-01 | GSE107591 | GEO

Homo sapiens

Project description:Identification and characterization of MCF01A circular RNAs [ChIP-seq]

| PRJNA290558 | ENA

Genome-wide identification of circular RNAs in eIF4A3 IP

Project description:Genome-wide identification of circular RNAs in eIF4A3 IP

| PRJNA1001827 | ENA