Project description:The ACP02 cell line was stablished from a primary diffuse adenocarcinoma (T3N2M0) and AGP01 cell was established from ascitic fluid cells from intestinal gastric adenocarcinoma (T3N2M1). mRNA samples from cell lines were amplified, labeled, and hybridized to the Affymetrix GeneChip Human Exon 1.0 ST array. The chip array data analysis was performed with Partek® software (http://www.partek.com).
Project description:Identification of the microRNA signature associated with human gastric adenocarcinoma. Total RNA obtained from 60 primary gastric cancer tissues and 8 surrounding non-cancer tissues was used for microarray analysis. For validation, real-time RT-PCR was performed.
Project description:Regulatory elements in cancer remain poorly characterized in primary solid tumors. Here we applied microscale histone modification profiling to delineate the landscape of somatic promoters and enhancers in primary gastric adenocarcinoma, analyzing 94 epigenomic profiles of primary tumors, normal tissues, and cell lines
Project description:Regulatory elements in cancer remain poorly characterized in primary solid tumors. Here we applied microscale histone modification profiling to delineate the landscape of somatic promoters and super-enhancers in primary gastric adenocarcinoma, analyzing 94 epigenomic profiles of primary tumors, normal tissues, and cell lines
Project description:Regulatory elements in cancer remain poorly characterized in primary solid tumors. Here we applied microscale histone modification profiling to delineate the landscape of somatic promoters and super-enhancers in primary gastric adenocarcinoma, analyzing 94 epigenomic profiles of primary tumors, normal tissues, and cell lines
Project description:Regulatory elements in cancer remain poorly characterized in primary solid tumors. Here we applied microscale histone modification profiling to delineate the landscape of somatic promoters and super-enhancers in primary gastric adenocarcinoma, analyzing 94 epigenomic profiles of primary tumors, normal tissues, and cell lines
Project description:Regulatory elements in cancer remain poorly characterized in primary solid tumors. Here we applied microscale histone modification profiling to delineate the landscape of somatic promoters and super-enhancers in primary gastric adenocarcinoma, analyzing 94 epigenomic profiles of primary tumors, normal tissues, and cell lines
Project description:Herein, we aimed to analyze the gene expression profile of medulloblastoma samples from a Brazilian cohort of 17 pediatric patients.