Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RRBS of sorted myeloid cells from tet mutant zebrafish embryos

ABSTRACT: RRBS of sorted myeloid cells from tet mutant zebrafish embryos

PROVIDER: PRJNA681863 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR13176120.fastq.gz	Fastqsanger.gz
	SRR13176121.fastq.gz	Fastqsanger.gz
	SRR13176122.fastq.gz	Fastqsanger.gz

Items per page:

1 - 3 of 3

Similar Datasets

RNA Sequencing and RRBS of sorted myeloid cells from tet mutant zebrafish embryos

Project description:RNA Sequencing and RRBS of sorted myeloid cells from tet mutant zebrafish embryos

| PRJNA681859 | ENA

RRBS of sorted myeloid cells from tet mutant zebrafish embryos

Project description:We report overexpression of socs3b leading to reduced cytokine signalling but no change in DNA methylation at this site

2020-12-02 | GSE162431 | GEO

RNA Sequencing and RRBS of sorted myeloid cells from tet mutant zebrafish embryos

Project description:This SuperSeries is composed of the SubSeries listed below.

2020-12-02 | GSE162435 | GEO

RNA Sequencing of sorted neutrophils cells from tet mutant zebrafish embryos

Project description:RNA Sequencing of sorted neutrophils cells from tet mutant zebrafish embryos

| PRJNA681861 | ENA

BS-seq of Tet-TKD 2-cell embryos

Project description:whole genome bisulfite sequencing of single control and Tet-TKD 2-cell embryos

2021-11-22 | GSE156006 | GEO

BS-seq of Tet-TKD 2-cell embryos

Project description:BS-seq of Tet-TKD 2-cell embryos

| PRJNA656300 | ENA

Impact of Tet inhibition by Bobcat339 on gene expression of porcine parthenogenetic embryos

Project description:To explore the effects of Tet on porcine pre-implantation embryogenesis, we utilized Bobcat339, a specific small-molecule inhibitor of the Tet protein, to treat parthenogenetic 4-cell stage embryos.

2023-12-30 | GSE218707 | GEO

Reduced Representational Bisulfite Sequencing of R1 and Dnmt1 Tet/Tet mouse embryonic stem cell lines

Project description:We generated RRBS data to enable a comparative DNA methylation analysis of Dnmt1 Tet/Tet, a mouse embyonic stem cell line (ESC) that overexpresses DNMT1 and the WT R1 ESCs and their neuronal derivatives. The optimized data analysis workflows provides a framework for comparative investigations of methylation profiles. This platform offers a comprehensive and more accurate quantitative and qualitative evaluation of methylated cytosines in ESCs and neurons. We expect that RRBS-based methylome analysis permits to understand the epigenetic basis of abnormal neurogenesis.

2020-09-18 | GSE152817 | GEO

Acute loss of TET function results in aggressive myeloid cancer in mice [RNA-Seq]

Project description:TET-family dioxygenases oxidize 5-methylcytosine (5mC) in DNA, and exert tumor suppressor activity in many types of cancers. Even in the absence of TET coding region mutations, TET loss-of-function is strongly associated with cancer. We show that acute elimination of TET function induces the rapid development of an aggressive, fully-penetrant and cell-autonomous myeloid leukemia in mice, pointing to a causative role for TET-loss-of-function in this myeloid malignancy. Phenotypic and transcriptional profiling showed aberrant differentiation of hematopoietic stem/ progenitor cells, impaired erythroid and lymphoid differentiation and strong skewing to the myeloid lineage, with only a mild relation to changes in DNA modification. We also observed progressive accumulation of DNA damage and strong impairment of DNA break repair, suggesting a key role for TET proteins in maintaining genomic integrity.

2015-11-26 | GSE72628 | GEO

Tet

Project description:Drosophila melanogaster Tet, Ten-Eleven Translocation (TET) family protein, is expressed in 4 baseline experiment(s);

| FBgn0263392 | ExpressionAtlas