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Transcriptome analysis of myeloma cells after IRF3 depletion by shRNAs

ABSTRACT: Transcriptome analysis of myeloma cells after IRF3 depletion by shRNAs

PROVIDER: PRJNA686371 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR13272100_1.fastq.gz	Fastqsanger.gz
	SRR13272100_2.fastq.gz	Fastqsanger.gz
	SRR13272101_1.fastq.gz	Fastqsanger.gz
	SRR13272101_2.fastq.gz	Fastqsanger.gz
	SRR13272102_1.fastq.gz	Fastqsanger.gz

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Transcriptome analysis of myeloma cells after IRF3 depletion by shRNAs

Project description:Whole transcriptome of IRF3-depleted myeloma cells was analysed using a high-throughput RNA-seq approach. IRF3 was depleted by 2 different shRNAs in MM1.S cells, and total RNA was isolated on day 4 post-lentiviral transduction. Poly A-tail enriched RNA was sequenced and the analysis of commonly regulated genes by both shRNAs from 2 independent experiments revealed that IRF3 regulates genes that are involved in cell cycle regulation.

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