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Expression data from wild type and Bach1 knock out ventral mid brains of two month old mice.

ABSTRACT: Expression data from wild type and Bach1 knock out ventral mid brains of two month old mice.

PROVIDER: PRJNA690564 | ENA |

REPOSITORIES: ENA

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Expression data from wild type and Bach1 knock out ventral mid brains of two month old mice.

Project description:Bach1 is a known repressor of NRF2 transcription factor which governs oxidative stress during pathophysiology of Parkinson's disease. NRF2 activation in ventral midbrain is associated with protection against oxidative stress induced apoptosis of DA neurons. In this study we hve evaluated the effect of loss of Bach1 fucntion in ventral mid brains.

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Genome-wide map of BACH1 binding in HEK 293T cells

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