Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Reconstitution of miR-550a-3p in diffuse malignant peritoneal mesothelioma cell line

ABSTRACT: Reconstitution of miR-550a-3p in diffuse malignant peritoneal mesothelioma cell line

PROVIDER: PRJNA694134 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

Reconstitution of miR-550a-3p in diffuse malignant peritoneal mesothelioma cell line

Project description:We aimed at analyzing the transcriptome changes associated with the reconstitution of miR-550a-3p in STO cells.

2021-01-23 | GSE165341 | GEO

Gene expression profiling of diffuse malignant peritoneal mesothelioma

Project description:Diffuse malignant peritoneal mesothelioma (DMPM) is a rapidly lethal malignancy. The comprehension of the molecular features of DMPM is of utmost importance for the fruitful management of the disease, especially in patients who fail standard treatments and have a poor prognosis due to the lack of effective alternative therapeutic options.

2019-02-07 | GSE112154 | GEO

Gene expression profiling of diffuse malignant peritoneal mesothelioma

Project description:Gene expression profiling of diffuse malignant peritoneal mesothelioma

| PRJNA439682 | ENA

Molecular subtypes of malignant peritoneal mesothelioma

Project description:Malignant Peritoneal Mesothelioma (PeM) is a rare but frequently fatal cancer that originates from the peritoneal lining of the abdomen. Standard treatment of PeM is limited to cytoreductive surgery and/or chemotherapy, and no targeted therapies for PeM yet exist. This study performs comprehensive integrative analysis of genome, transcriptome, and proteome of treatment-naïve PeM tumors with the aim of identifying mesothelioma-related molecular alterations and potentially identifying novel treatment strategies.

2018-12-11 | PXD008873 | Pride

microRNA expression profiling in diffuse malignant peritoneal mesothelioma

Project description:Diffuse malignant peritoneal mesothelioma (DMPM) is a rapidly lethal malignancy. The comprehension of the molecular and cellular features of DMPM is of utmost importance for the fruitful management of the disease, especially in patients who fail standard treatments and have a poor prognosis due to the lack of effective alternative therapeutic options. In this context, we previously found that telomerase activity (TA), which accounts for the limitless proliferative potential of cancer cells, is prognostic for disease relapse and cancer-related death in DMPM patients. Consequently, the identification of factors involved in telomerase activation/regulation may pave the way towards the development of novel therapeutic interventions for the disease. In the present study, miRNA expression profiling was carried out in a series of DMPM tissue specimens, previously characterized for the occurrence of TA, in order to possibly identify miRNAs that may play a role in the establishment/regulation of such a telomere maintenance mechanism in this malignancy and consequently furnish a biological rationale for the possible future development of miRNA-based telomerase-targeted therapeutic approaches.

2017-08-11 | GSE99362 | GEO

Gene Expression Profiling of Malignant Peritoneal Mesothelioma Patient Tumor Samples

2010-09-27 | GSE15627 | GEO

Gene Expression Profiling of Malignant Peritoneal Mesothelioma Patient Tumor Samples

Project description:Gene expression profiles were generated from 41 consecutive surgically resected fresh frozen malignant peritoneal mesothelioma patient tumor samples to identify molecular prognostic factors. Patient tumor samples hybridized against the common reference (complementary DNA generated from human universal RNA), 41 tumor samples.

2010-09-27 | E-GEOD-15627 | biostudies-arrayexpress

RNA-seq analysis of MES-MM 98 and REN mesothelioma cell lines modulated for miR-24-3p expression

Project description:Identification of relevant miR-24-3p target mRNAs in human mesothelioma cell lines in order to characterize novel therapeutical targets in Mesothelioma disease

2019-02-13 | E-MTAB-7079 | biostudies-arrayexpress

Molecular subtypes of malignant peritoneal mesothelioma

Project description:Malignant Peritoneal Mesothelioma (PeM) is a rare but frequently fatal cancer that originates from the peritoneal lining of the abdomen. Standard treatment of PeM is limited to cytoreductive surgery and/or chemotherapy, and no targeted therapies for PeM yet exist. This study performs comprehensive integrative analysis of genome, transcriptome, and proteome of treatment-naive PeM tumors with the aim of identifying mesothelioma-related molecular alterations and potentially identifying novel treatment strategies.

| EGAS00001002820 | EGA

Spectral histopathology supported laser capture microdissection and quantitative proteome analysis of diffuse malignant mesothelioma

Project description:FTIR based spectral histopathology was used for label-free classification of tumor tissue sections. The regions of interest were identified and annotated with high spatial resolution. The spatial information was used for automated laser capture microdissection of relevant tissue areas. Subsequently, the collected tissue samples were analyzed using quantitative proteomics. This novel approach for precise sample collection in clinical studies was applied to differentiate epitheloid and sarcomatoid subtypes of diffuse malignant mesothelioma.

2017-03-31 | PXD004818 | Pride

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data