Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Effect of Smoke Dye Exposure in Zebrafish Embryos

ABSTRACT: Effect of Smoke Dye Exposure in Zebrafish Embryos

PROVIDER: PRJNA700095 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR13646800_1.fastq.gz	Fastqsanger.gz
	SRR13646800_2.fastq.gz	Fastqsanger.gz
	SRR13646801_1.fastq.gz	Fastqsanger.gz
	SRR13646801_2.fastq.gz	Fastqsanger.gz
	SRR13646802_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 186

Similar Datasets

Effect of Smoke Dye Exposure in Zebrafish Embryos

Project description:Whole transcriptome analysis of dechorinated zebrafish embryos after (static?) exposure to one of five smoke dyes from 6 hours post-fertilization (hpf) to 48 hpf. Smoke dyes tested are Disperse Blue 14, Disperse Red 9, Solvent Red 169, Solvent Violet 47, and Solvent Yellow 33. Results provide insight into the molecular mechanisms of immunological response to the dyes.

2021-02-07 | GSE166302 | GEO

MeHg exposure zebrafish embryos vs control

Project description:Gene respons in the central nervous system of zebrafish embryos exposed to the neurotoxicant methyl mercury Two-condition experiment, control vs MeHg exposure embryos (60 Âµg/l), Biological replicates: 4, dye swaps

2012-05-14 | E-GEOD-37970 | biostudies-arrayexpress

Developmental, Behavioral and Transcriptomic Changes in Zebrafish Embryos after Smoke Dye Exposure.

Project description:(1) Background: Disperse Blue 14, Disperse Red 9, Solvent Red 169 and Solvent Yellow 33 have been used to color smoke; however, they have not been comprehensively assessed for their potential health hazards. (2) Methods: To assess the effects of these dyes, zebrafish embryos were exposed from 6 to 120 h post fertilization (hpf) to 10-55 µM Disperse Red 9, 1-50 µM Solvent Red 169, 7.5-13.5 µM Solvent Yellow 33 or 133-314 µM Disperse Blue 14. Embryos were monitored for adverse effects on gene expression at 48 hpf as well as for mortality, development and behavior at 120 hpf. The dyes were examined for their potential to cross the blood-brain barrier. (3) Results: Solvent Yellow 33 and Disperse Blue 14 impaired development and behavior at all concentrations. Disperse Red 9 impaired behavior at all concentrations and development at all concentrations except for 10 µM. Solvent Red 169 caused no effects. Mortality was only seen in Disperse Blue 14 at 261.5 and 314 µM. Gene expression indicated impacts on neurodevelopment and folate and retinol metabolism as potential mechanisms of toxicity. (4) Conclusions: Smoke dyes have a high potential for causing developmental changes and neurotoxicity and should be examined more closely using comprehensive approaches as used here.

| S-EPMC9171585 | biostudies-literature

Chlorpyrifos exposure zebrafish embryos

Project description:Zebrafish embryos have been exposed to Chlorpyrifos from 24 to 48 hours post fertilization

2016-10-14 | GSE88704 | GEO

Aroclor exposure zebrafish embryos

Project description:Zebrafish embryos have been exposed to Aroclor 1254 from 24 to 48 hours post fertilization

2016-10-14 | GSE88703 | GEO

MicroRNA expression profiling after short-term exposure to TCDD in zebrafish embryos

Project description:This SuperSeries is composed of the following subset Series: GSE38839: MicroRNA expression profiling after short-term exposure to TCDD in zebrafish embryos [agilent and exiqon array data] GSE39808: MicroRNA expression profiling after short-term exposure to TCDD in zebrafish embryos [miRNA-Seq data] Refer to individual Series

2012-08-01 | E-GEOD-39809 | biostudies-arrayexpress

Concentration dependent gene expression in zebrafish embryos after PCE exposure

Project description:The dataset contained concentration course exposures of 24hpf old zebrafish embryos with tetrachloroethylene (PCE). The exposure duration was set to 12h and 24h and the concentrations were chosen to be not higher than the LC10.

2019-01-31 | GSE63994 | GEO

MeHg exposure zebrafish embryos vs control

Project description:Gene respons in the central nervous system of zebrafish embryos exposed to the neurotoxicant methyl mercury

2012-05-15 | GSE37970 | GEO

Whole-genome expression profile in zebrafish embryos after chronic exposure to morphine

Project description:A great number of studies have investigated changes induced by morphine exposure in gene expression using several experimental models. In this study, we examined gene expression changes during chronic exposure to morphine during maturation and differentiation of zebrafish CNS. Our study identified different functional classes of genes and individual candidates involved in the mechanisms underlying susceptibility to morphine actions related to CNS development. These results open new lines to study the treatment of pain and the molecular mechanisms involved in addiction. We also found a set of zebrafish-specific morphine-induced genes, which may be putative targets in human models for addiction and pain processes. Zebrafish embryos were divided into two experimental groups: control embryos and embryos at 5 hpf exposed to 10 nM morphine and collected at 24 hpf (covering the complete embryogenesis). Morphine was administered to the embryos in their water environment, i.e., diluted in E3 embryonic medium. The exposition to begun at the stage of 5 hpf (end of blastula) is continuous, in order to study the chronic effects of the exposure to drug. Microarray experiments were performed using six replicates for each condition, which contained the RNA of approximately one hundred embryos to minimize the influence of potential individual differences between the animals and technical variation introduced by tissue preparation. We previously reported that a concentration of 10 nM morphine is the highest concentration that can be used without a toxic effect on the embryos, and close to 5% of the morphine diluted in the E3 medium is detected in the embryo.

2014-09-04 | E-GEOD-61062 | biostudies-arrayexpress

hBD2 in Murine Cigarette Smoke Exposure

Project description:hBD2 in Murine Cigarette Smoke Exposure

| PRJNA766626 | ENA