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Homo sapiens isolate:breast cancer patients

ABSTRACT: Homo sapiens isolate:breast cancer patients Genome sequencing

PROVIDER: PRJNA701540 | ENA |

REPOSITORIES: ENA

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Homo sapiens isolate:breast cancer

Project description:Homo sapiens isolate:breast cancer Genome sequencing

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miRNA expression profiling in early stage breast cancer

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2012-02-02 | E-GEOD-31309 | biostudies-arrayexpress

caArray_gray-00248: Genomic and transcriptional aberrations linked to breast cancer pathophysiologies

Project description:We measured baseline gene expression profiles for a set of breast tumors. gray-00248 Assay Type: Gene Expression Provider: Affymetrix Array Designs: U133AAofAv2 Organism: Homo sapiens (ncbitax) Tissue Sites: mammary gland Material Types: synthetic_RNA, total_RNA Disease States: breast cancer

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Project description:MicroRNAs (miRNAs) are known to be deregulated in human breast cancer (BC). The purpose of the current study was to investigate the expression of miRNAs in different stages of BC to assess their biological value in BC progression. MiRNA expression was assessed in a series of BC patients (n=7) with distinct stages of tumour progression (Normal, in-situ (DCIS), primary invasive BC and nodal metastases) to evaluate miRNA differential expression. We used an Agilent miRNA microarray based platform which uses miRBase 16 to screen for 1205 Homo sapiens (hsa) and 144 human viral miRNA candidates. To validate the microarray data, the expression of two deregulated miRNAs was measured by TaqMan quantitative real-time reverse transcription polymerase chain reaction (qRT-PCR).

2012-06-23 | GSE38867 | GEO

caArray_geral-00143: An estrogen receptor-negative breast cancer subset characterized by a hormonally regulated transcriptional program and response to androgen

Project description:Clinical heterogeneity of esrtrogen receptor-negative, progesterone receptor-negative [ER(-)/PR(-)] breast cancer (BC) suggests biological heterogeneity. We performed gene expression analysis of primary BCs and BC cell lines to identify the underlying biology of ER(-)/PR(-) disease, define subsets, and identify potential therapeutic targets. geral-00143 Assay Type: Gene Expression Provider: Affymetrix Array Designs: HG-U133A Organism: Homo sapiens (ncbitax) Material Types: cRNA, cell, OrganismPart, whole_organism, total_RNA Disease States: breast carcinomas

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Project description:PBMCs from metastatic breast cancer patients

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caArray_gray-00215: A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

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2015-05-19 | E-GEOD-69017 | biostudies-arrayexpress

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