Project description:Domestication of pig results in modifications of many traits, including fatness traits, which are important in pig production since they have effect on meat quality, fattening efficiency, reproduction and immunity.In this study, we investigate 3D genome organization and transcriptomic characterization of adipose tissues (ATs) between wild boars and Bama pig, a typical indigenous domestic pig in China, to uncover molecular mechanisms of fatness-phenotypic shifts.

2022-01-14 | GSE183447 | GEO

Total RNA sequencing in multiple Sus Scrofa tissues reveals novel long non-coding RNAs functioning in skeletal muscle development

Project description:Long non-coding RNAs (lncRNAs) play important roles in diverse biological processes. However, the landscape of lncRNAs is largely unclear in Sus scrofa. Here we performed stranded RNA-seq on total RNA libraries from over 100 samples of Sus scrofa tissues. We identified 10,813 lncRNAs in Sus scrofa, of which 9,075 are novel. 57% of these lncRNAs were conserved in both human and mouse. These conserved lncRNAs tend to be more tissue-specific than pig-specific lncRNAs, and enriched in reproducible organs (i.e. testis and ovary). We characterized a group of lncRNAs potentially involved in the skeletal muscle development. One such lncRNA, a homolog of maternally expressed gene 3 (MEG3), was specifically expressed in the skeletal muscle at early developmental stage. And its expression pattern is conserved in pig and mouse. By over-expressing and knocking down MEG3 in mouse myoblast cell lines, we demonstrated its novel function as a myoblast proliferation suppressor.

2017-02-09 | GSE73763 | GEO

Sus scrofa scrofa breed:Huai pig

Project description:Sus scrofa scrofa breed:Huai pig Genome sequencing

| PRJNA1147173 | ENA

Sus scrofa scrofa breed:Mini-pig

Project description:Sus scrofa scrofa breed:Mini-pig Raw sequence reads

| PRJNA374593 | ENA

Sus scrofa scrofa breed:Kele pig

Project description:Sus scrofa scrofa breed:Kele pig Raw sequence reads

| PRJNA930985 | ENA

Sus scrofa scrofa breed:Kele pig

Project description:Sus scrofa scrofa breed:Kele pig Transcriptome or Gene expression