Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Simultaneous profiling of multiple chromatin proteins in the same cells

ABSTRACT: Simultaneous profiling of multiple chromatin proteins in the same cells

PROVIDER: PRJNA720083 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR14150915_1.fastq.gz	Fastqsanger.gz
	SRR14150915_2.fastq.gz	Fastqsanger.gz
	SRR14150917_1.fastq.gz	Fastqsanger.gz
	SRR14150917_2.fastq.gz	Fastqsanger.gz
	SRR14150918_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 42

Similar Datasets

Simultaneous profiling of multiple chromatin proteins in the same cells

Project description:Methods derived from CUT&RUN and CUT&Tag enable genome-wide mapping of the localization of proteins on chromatin from as few as one cell. These and other mapping approaches focus on one protein at a time, preventing direct measurements of co-localization of different chromatin proteins in the same cells and requiring prioritization of targets where samples are limiting. Here we describe multi-CUT&Tag, an adaptation of CUT&Tag that overcomes these hurdles by using antibody-specific barcodes to simultaneously map multiple proteins in the same cells. Highly specific multi-CUT&Tag maps of histone marks and RNA Polymerase II uncovered sites of co-localization in the same cells, active and repressed genes, and candidate cis-regulatory elements. Single-cell multi-CUT&Tag profiling facilitated identification of distinct cell types from a mixed population and inference of cell type-specific gene expression. In sum, multi-CUT&Tag increases the “per cell” information content of epigenomic maps, facilitating direct analysis of the interplay of different proteins on chromatin.

2021-09-06 | GSE171554 | GEO

Spatial-Mux-seq: Multiplexed spatial mapping of chromatin features, transcriptome, and proteins at tissue scale

Project description:we present a multi-modal spatial technology that allows simultaneous profiling of four different modalities, including multi epigenomic modalities (any combination of two histone modifications and open chromatin at the same time), whole transcriptome, and a panel of proteins at tissue scale and cellular level in a spatially resolved manner.

2024-10-22 | GSE263333 | GEO

NEAT-seq: Simultaneous profiling of intra-nuclear proteins, chromatin accessibility, and gene expression in single cells

Project description:NEAT-seq: Simultaneous profiling of intra-nuclear proteins, chromatin accessibility, and gene expression in single cells

| PRJNA740041 | ENA

Chromatin integration labeling for mapping multiple DNA binding proteins and modifications with low input.

Project description:Chromatin integration labeling for mapping multiple DNA binding proteins and modifications with low input.

| PRJNA590476 | ENA

Targeted resequencing of ribosomal proteins in multiple myeloma patient samples.

Project description:We studied 38 multiple myeloma samples to discover mutations in ribosomal proteins. To this end, we ran a specifically designed targeted resequencing study to resequence the coding regions of all ribosomal proteins.

| EGAS00001002405 | EGA

Same lang

Project description:Same lang Raw sequence reads

| PRJNA1117086 | ENA

Simultaneous profiling of chromatin architecture and transcription in single cells

Project description:Simultaneous profiling of chromatin architecture and transcription in single cells

| PRJNA870095 | ENA

Simultaneous profiling of transcriptome and chromatin accessibility in single nucleus

Project description:Simultaneous profiling of transcriptome and chromatin accessibility in single nucleus

| PRJNA520914 | ENA

Mouse embryonic stem cells can differentiate via multiple paths to the same state

Project description:Mouse embryonic stem cells can differentiate via multiple paths to the same state