Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Sequencing of chronic myeloid leukemia (CML) cell lines upon upregulation or downregulation of G0/G1 switch gene (G0S2)

ABSTRACT: Sequencing of chronic myeloid leukemia (CML) cell lines upon upregulation or downregulation of G0/G1 switch gene (G0S2)

PROVIDER: PRJNA721438 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR14217412_1.fastq.gz	Fastqsanger.gz
	SRR14217412_2.fastq.gz	Fastqsanger.gz
	SRR14217413_1.fastq.gz	Fastqsanger.gz
	SRR14217413_2.fastq.gz	Fastqsanger.gz
	SRR14217414_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 18

Similar Datasets

Sequencing of chronic myeloid leukemia (CML) cell lines upon upregulation or downregulation of G0/G1 switch gene (G0S2)

Project description:Current treatment for CML involves tyrosine kinase inhibitors (TKIs), which turned it into a managable disease. In a transcriptional profile of TKI-resistant versus newly diagnosed CML patient samples, G0S2 was shown to be profoundly downregulated.

2021-04-13 | GSE171945 | GEO

Expression data of NIH3T3 in G0 and G1 phases

Project description:NIH3T3 in the middle of G0 to G1 transion consists of the cells which is still staying G0 phase and the cells which enters G1. Monitoring the expressions of p27 and Cdt1 enables to distinguish these two; p27+/Cdt1+ cells as the cells in G0 phase and p27-Cdt1+ cells as G1 phase We sorted p27+Cdt1+ (G0) NIH3T3 cells and p27-Cdt1+ (G1) NIH3T3 cells in the middle of G0-G1 transition, 5 hours after serum addition following the serum addition using mVenus-p27K- and mCherry-hCdt1(30/120) . We compared the expression profiles of these NIH3T3 cells in G0 and G1 phases and identified the genes upregulated in G0 or G1 phases.

2014-02-21 | GSE46511 | GEO

Expression data of NIH3T3 in G0 and G1 phases

2014-02-21 | E-GEOD-46511 | biostudies-arrayexpress

H2A.Z Mapping During G0/G1 and Mitosis

Project description:We report genome wide mapping of the histone variant H2A.Z during G0/G1 and mitosis in T24 bladder cancer cells. The results show that the broad enrichment pattern of H2A.Z near transcription start sites of active genes is maintained during mitosis. Furthermore, using H2A.Z localization to visualize nucleosome positioning near the start site, we see that the +1 nucleosome of active genes shifts upstream to occupy the transcription start sites during mitosis and the nucleosome depleted region is shortened. H2A.Z is also maintained on the -2 nucleosome which also shifts towrds the transcription start site during mitosis, further contributing to the shorteneing of the nucleosome depleted region. Examination of H2A.Z duing G0/G1 and mitosis in bladder cancer cells

2010-06-24 | E-GEOD-19568 | biostudies-arrayexpress

Quantification of membrane protein expression in G0 and G1 cell cycle phase samples in PC3 prostate cancer cells

Project description:Prostate cancer (PCa) has a significant ability to disseminate and survive in the bone marrow (BM). Once there, disseminated tumor cells (DTCs) may lie dormant for years, but often eventually reactivate proliferative pathways, thus largely contributing to bone metastasis, disease progression, and relapse. Unfortunately, quiescent PCa cells are difficult to identify and target with treatment, in part because formerly identified relevant markers are intracellular and regulated by protein stability. We sought to address this problem by identifying a G0 marker that is expressed on the cell surface and therefore amenable to antibody binding for identification and therapeutic targeting. In doing so, we utilized stably transduced fluorescent markers for CDKN1B (p27) and CDT1 protein levels, which separate viable PCa cells into G0, G1, or combined S/G2/M populations (as described in PMID 34957090). We then performed FACS to collect G1 and G0 PC3 PCa cells, isolated membrane proteins, and subsequently used GC-MS proteomics to determine differences in protein abundance between G0 and G1. In total, 3,791 proteins were identified.

2023-03-03 | PXD037378 | Pride

Differential expression analysis of HFF cells in G0 phase compared to cells in G1 using MAT

Project description:This SuperSeries is composed of the following subset Series: GSE36154: Expression analysis of HFF cells in G0 phase [MAT] GSE36155: Expression analysis of HFF cells in G1 phase [MAT] GSE36156: Differential expression analysis of HFF cells in G0 phase compared to cells in G1 [MAT] Refer to individual Series

2012-06-05 | E-GEOD-36187 | biostudies-arrayexpress

Differential expression analysis of HFF cells in G0 phase compared to cells in G1 using TileShuffle

Project description:This SuperSeries is composed of the following subset Series: GSE36162: Expression analysis of HFF cells in G0 phase [TileShuffle] GSE36163: Expression analysis of HFF cells in G1 phase [TileShuffle] GSE36164: Differential expression analysis of HFF cells in G0 phase compared to cells in G1 [TileShuffle] Refer to individual Series

2012-06-05 | E-GEOD-36190 | biostudies-arrayexpress

Differential expression analysis of HFF cells in G0 phase compared to cells in G1 [TAS]

Project description:Whole transcriptome differential expression analysis of HFF cells on Affymetrix Human Tiling 1.0 array set. Cells were synchronised by serum starvation and transcriptome-wide changes occurring at the transition from G0 phase to G1 phase detected. Expression data and fold changes were processed with Tiling Array Software (TAS). We analyzed one Affymetrix Human Tiling 1.0R set each for HFF cells in G0 phase and cells in G1 phase

2012-12-18 | E-GEOD-36160 | biostudies-arrayexpress

Differential expression analysis of HFF cells in G0 phase compared to cells in G1 [TileShuffle]

Project description:Whole transcriptome differential expression analysis of HFF cells on Affymetrix Human Tiling 1.0 array set. Cells were synchronised by serum starvation and transcriptome-wide changes occurring at the transition from G0 phase to G1 phase detected. Expression data and fold changes were processed with our new permutation approach TileShuffle variant B. We analyzed one Affymetrix Human Tiling 1.0R set each for HFF cells in G0 phase and cells in G1 phase

2012-12-18 | E-GEOD-36164 | biostudies-arrayexpress

Transcription profiling of human CD133-positive G0 and G1 human ubmbilical vein cells

Project description:To identify regulators of human HSC fate, we transcriptionally profiled quiescent primitive cord blood (CB) CD133+ G0 cells enriched for long term culture initiating cell (LTC-IC) activity. CD133+ G0 cells were sorted by cell cycle status using combined DNA and RNA staining; less immature CD133+G1 cells served as a comparison.

2008-03-06 | E-MEXP-1412 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data