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Fusarium oxysporum f. sp. lini

ABSTRACT: Genome sequencing of Fusarium oxysporum f. sp. lini strains of different virulence

PROVIDER: PRJNA721899 | ENA |

REPOSITORIES: ENA

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			Action	DRS
		Other
	SRR14237200_1.fastq.gz	Fastqsanger.gz
	SRR14237200_2.fastq.gz	Fastqsanger.gz
	SRR14237201_1.fastq.gz	Fastqsanger.gz
	SRR14237201_2.fastq.gz	Fastqsanger.gz

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Fusarium oxysporum f. sp. lini

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Project description:In plant pathogenic fungi, conditionally dispensable (CD) chromosomes are often associated with virulence, but not viability. Such virulence-associated CD chromosomes carry genes encoding effectors and/or host-specific toxin biosynthesis enzymes, potentially important for determining host specificity. Fusarium oxysporum causes devastating diseases of more than 100 plant species. In particular, F. oxysporum f. sp. conglutinans (Focn) can infect Brassicaceae plants including Arabidopsis and cabbage. Here we show that Focn has multiple CD chromosomes involving in not only virulence but also vegetative growth, which is an atypical feature of known CD chromosomes. Among them, we identified specific CD chromosomes that are required for virulence to either Arabidopsis, cabbage, or both. We revealed that a pair of effectors encoded in one of the CD chromosomes is required for suppression of the Arabidopsis-specific phytoalexin-based immunity. The effector pair is highly conserved in F. oxysporum isolates capable of infecting Arabidopsis. This study provides insights into how host specificity of F. oxysporum is determined by a pair of effector genes on a CD chromosome.

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Comparsion of histone modifications of core and accessory chromosomes of Fusarium oxysporum

Project description:To study whether there are differences in chromatin-mediated regulation between and within chromosomes in Fusarium oxysporum f. sp. lycopersici 4287 (FGSC9935), we determined the distribution of histone marks associated with euchromatin (H3K4me2) and facultative heterochromatin (H3K27me3) in vitro. We then determined whether these differences correlate with differences in dispensability and sequence divergence and gene expression.

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