Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA-seq analysis of mouse heart tissue ischemia/reperfusion (I/R)

ABSTRACT: RNA-seq analysis of mouse heart tissue ischemia/reperfusion (I/R)

PROVIDER: PRJNA723502 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR14293165_1.fastq.gz	Fastqsanger.gz
	SRR14293165_2.fastq.gz	Fastqsanger.gz
	SRR14293166_1.fastq.gz	Fastqsanger.gz
	SRR14293166_2.fastq.gz	Fastqsanger.gz
	SRR14293167_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 8

Similar Datasets

Proteome and SUMOylome of mouse heart tissue after ischemia and reperfusion

Project description:Here we provide proteome and SUMOylation patterns of proteins in the heart throughout ischemia and reperfusion. Moreover, we identify SUMO1 and SUMO2 target proteins in vivo

2021-09-09 | PXD021640 | Pride

Intralipid protects the heart in late pregnancy against ischemia/reperfusion injury

Project description:The heart of late pregnant (LP) rodents is more prone to ischemia/reperfusion (I/R) injury compared to non-pregnant rodents. We hypothesized that Intralipid (ITLD) protects the heart in LP rodents against I/R injury. We performed genome-wide expression profiling to identify the underlying mechanisms. Female LP rat hearts were subjected to ischemia followed by reperfusion with vehicle or ITLD (one bolus of 5mg/kg).

2016-02-09 | E-GEOD-77698 | biostudies-arrayexpress

Expression data from mouse heart tissue ischemia/reperfusion (I/R) treated for 0,24,48,72 hours

Project description:Expression data from mouse heart tissue ischemia/reperfusion (I/R) treated for 0,24,48,72 hours

| PRJNA673424 | ENA

RNA-seq analysis of mouse heart tissue ischemia/reperfusion (I/R)

Project description:Myocardial Ischemia-reperfusion injury is a serious clinical problem that lacks effective therapy. However, the precise mechanism leading to myocardial I/R injury remains unclear.Our study defined the dynamic changes of the differentially expressed genes related myocardial I/R injury, and provide basis for comprehensive understanding of the disease at molecular level. We investigated schemia-reperfusion –mediated gene expression alteration associated with the development of cardiac injury by RNA-seq in a mouse model.

2021-04-22 | GSE172480 | GEO

Gene Expression Changes due to Rat Lung Ischemia-Reperfusion Injury

Project description:Ischemia-reperfusion injury (IRI) is a major cause of morbidity and mortality following conventional lung transplantation and warm ischemia may limit success of transplanting lungs from non-heart-beating donors. We sought to determine alterations in gene expression in rat lung tissue subjected to warm ischemia in vivo followed by reperfusion. Keywords: time course

2019-04-30 | GSE9634 | GEO

Expression data from mouse heart tissue ischemia/reperfusion (I/R) treated for 0,24,48,72 hours

Project description:Myocardial Ischemia-reperfusion injury is a serious clinical problem that lacks effective therapy.However, the precise mechanism leading to myocardial I/R injury remains unclear.Our study defined the dynamic changes of the differentially expressed genes related myocardial I/R injury, and provide basis for comprehensive understanding of the disease at molecular level. We investigated schemia-reperfusion –mediated gene expression alteration associated with the development of cardiac injury by microarray in a mouse model.

2020-10-31 | GSE160516 | GEO

Differential analysis of transcriptomes regulated upon ischemic preconditioning and postconditioning versus ischemia-reperfusion protocols in the mouse heart in vivo

Project description:Ischemic preconditioning (PreC) and postconditioning (PostC) are the most potent cardioprotective strategies inhibiting ischemia-reperfusion (IR) injuries.The aim of our study was to identify the gene profiles regulated upon preconditioning and postconditioning in the mouse heart in vivo.

2012-01-06 | GSE31296 | GEO

Global microRNA expression profiling of mouse livers following ischemia-reperfusion injury at different stages. [miRNA]

Project description:Hepatic ischemia reperfusion injury is a dynamic process consisting of two stages: ischemia and reperfusion, and triggers a cascade of physiological and biochemical events. Given the important role of microRNAs in regulating gene expression, we analyzed gene expression changes in mouse livers at sham control, ischemia stage, and reperfusion stage. We generated global expression profiles of microRNA and mRNA genes in mouse livers subjected to ischemia reperfusion injury at the three stages, respectively. Comparison analysis showed that reperfusion injury had a distinct expression profile whereas the ischemia sample and the sham control were clustered together. Consistently, there are 69 differentially expressed microRNAs between the reperfusion sample and the sham control whereas 28 differentially expressed microRNAs between the ischemia sample and the sham control. We further identified two modes of microRNA expression changes in ischemia reperfusion injury. Functional analysis of both the differentially expressed microRNAs in the two modes and their target mRNAs revealed that ischemia injury impaired mitochondria function, nutrient consumption, and metabolism process. In contrast, reperfusion injury led to severe tissue inflammation that is predominantly an innate-immune response in the ischemia reperfusion process. Our staged analysis of gene expression profiles provides new insights into regulatory mechanisms of microRNAs in mouse hepatic ischemia reperfusion injury.

2015-10-01 | GSE72314 | GEO

Global microRNA expression profiling of mouse livers following ischemia-reperfusion injury at different stages. [mRNA]

2015-10-01 | GSE72312 | GEO

Intralipid protects the heart in late pregnancy against ischemia/reperfusion injury

2016-02-09 | GSE77698 | GEO