Project description:The genome-wide analysis was carried out to find out the genes responsible for single and multiple stress in Shigella flexneri 2a str. 2457T. This result can be offered to explain bacterial responses, such as the capacity to survive and elicit infections.
Project description:The genome-wide analysis was carried out to find out the genes responsible for single and multiple stress in Shigella flexneri 2a str. 2457T. E. coli used as a reference strain. This is RNA-seq data of E.coli K-12 MG1655.
Project description:The genome-wide analysis were carried out to find out the genes reponsible for single and multiple stress in Shigella flexneri 2a str. 2457T. This results can be offered to explain bacterial responses such as the capacity of survive and elicit infections.
Project description:We evaluated the transcriptome changes induced by infection of Hela 229 cells with Shigella flexneri. The sample set consists of a control (mock), total population of infected sample and infected sample sorted into Shigella positive and Shigella negative population.
Project description:Berberine is a natural isoquinoline alkaloid found in Chinese medicinal herbs which is active against a variety of microbial infections. To examine the potential effects of berberine on Shigella flexneri, a whole-genome DNA microarray was constructed and transcriptome analysis of the cellular responses of S.flexneri when exposed to Berberine Chloride (BC) was performed.
Project description:To find the alterations of expression profiles of shigella flexneri, we performed DNA chip analysis and proteomic analysis at the same time.
