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Differences in vaginal microbiota, host transcriptome and proteins in women with bacterial vaginosis are associated with metronidazole treatment response

ABSTRACT: Differences in vaginal microbiota, host transcriptome and proteins in women with bacterial vaginosis are associated with metronidazole treatment response

PROVIDER: PRJNA731542 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR14608700.fastq.gz	Fastqsanger.gz
	SRR14608900.fastq.gz	Fastqsanger.gz
	SRR14609000.fastq.gz	Fastqsanger.gz
	SRR14609100.fastq.gz	Fastqsanger.gz
	SRR14608701.fastq.gz	Fastqsanger.gz

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Differences in vaginal microbiota, host transcriptome and proteins in women with bacterial vaginosis are associated with metronidazole treatment response

Project description:Bacterial vaginosis (BV) treatment failures or recurrences are common. To identify features associated with treatment response, we compared vaginal microbiota and host ectocervical transcriptome before and after oral metronidazole therapy. Response to metronidazole is characterized by significant changes in chemokines and related transcripts suggesting that strategies to promote these pathways may prove beneficial.

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Project description:Differences in vaginal microbiota, host transcriptome and proteins in women with bacterial vaginosis are associated with metronidazole treatment response

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